1 to 5 of 5 literature results

• Methylation of histone H3R2 by PRMT6 and H3K4 by an MLL complex are mutually exclusive.

  Eukaryotic genomes are organized into active (euchromatic) and inactive (heterochromatic) chromatin domains. Post-translational modifications of histo…

  Authors: Ernesto Guccione, Christian Bassi, Fabio Casadio, Francesca Martinato, Matteo Cesaroni, Henning Schuchlautz, Bernhard Lüscher, Bruno Amati

  Source: Nature. 2007 Oct 18

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• Tip60 is a haplo-insufficient tumour suppressor required for an oncogene-induced DNA damage response.

  The acetyl-transferase Tip60 might influence tumorigenesis in multiple ways. First, Tip60 is a co-regulator of transcription factors that either promo…

  Authors: Chiara Gorrini, Massimo Squatrito, Chiara Luise, Nelofer Syed, Daniele Perna, Landon Wark, Francesca Martinato, Domenico Sardella, Alessandro Verrecchia, Samantha Bennett,…

  Source: Nature. 2007 Aug 30

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• Myc-binding-site recognition in the human genome is determined by chromatin context.

  Large-scale chromatin immunoprecipitation (ChIP) studies have been effective in unravelling the distribution of DNA-binding transcription factors alon…

  Authors: Ernesto Guccione, Francesca Martinato, Giacomo Finocchiaro, Lucilla Luzi, Laura Tizzoni, Valentina Dall' Olio, Giuseppe Zardo, Clara Nervi, Loris Bernard, Bruno Amati

  Source: Nature cell biology. 2006 Jul

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• A positive role for Myc in TGFbeta-induced Snail transcription and epithelial-to-mesenchymal transition.

  Myc and transforming growth factor-beta (TGFbeta) signaling are mutually antagonistic, that is Myc suppresses the activation of TGFbeta-induced genes,…

  Authors: A P Smith, A Verrecchia, G Fagà, M Doni, D Perna, F Martinato, E Guccione, B Amati

  Source: Oncogene. 2009 Jan 22

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• Analysis of Myc-induced histone modifications on target chromatin.

  The c-myc proto-oncogene is induced by mitogens and is a central regulator of cell growth and differentiation. The c-myc product, Myc, is a transcript…

  Authors: Francesca Martinato, Matteo Cesaroni, Bruno Amati, Ernesto Guccione

  Source: PloS one. 2008

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