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• An injected bacterial effector targets chromatin access for transcription factor NF-kappaB to alter transcription of host genes involved in immune responses.

  Phosphorylation of histone H3 at Ser10 increases chromatin accessibility to transcription factor NF-kappaB on a subset of genes involved in immune res…

  Authors: Laurence Arbibe, Dong Wook Kim, Eric Batsche, Thierry Pedron, Bogdan Mateescu, Christian Muchardt, Claude Parsot, Philippe J Sansonetti

  Source: Nature immunology. 2007 Jan

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• Anthrax lethal toxin impairs IL-8 expression in epithelial cells through inhibition of histone H3 modification.

  Lethal toxin (LT) is a critical virulence factor of Bacillus anthracis, the etiological agent of anthrax, whose pulmonary form is fatal in the absence…

  Authors: Benoit Raymond, Eric Batsche, Florence Boutillon, Yong-Zheng Wu, Dominique Leduc, Viviane Balloy, Eloïse Raoust, Christian Muchardt, Pierre L Goossens, Lhousseine Touqui

  Source: PLoS pathogens. 2009 Apr

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• Human BAHD1 promotes heterochromatic gene silencing.

  Gene silencing via heterochromatin formation plays a major role in cell differentiation and maintenance of homeostasis. Here we report the identificat…

  Authors: Hélène Bierne, To Nam Tham, Eric Batsche, Anne Dumay, Morwenna Leguillou, Sophie Kernéis-Golsteyn, Béatrice Regnault, Jacob S Seeler, Christian Muchardt, Jean Feunteun,…

  Source: Proceedings of the National Academy of Sciences of the United States of America. 2009 Aug 18

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