1 to 10 of 22 literature results

• The opposite effects of IL-15 and IL-21 on CLL B cells correlate with differential activation of the JAK/STAT and ERK1/2 pathways.

  The clonal expansion of chronic lymphocytic leukemia (CLL) cells requires the interaction with the microenvironment and is under the control of severa…

  Authors: Daniela de Totero, Raffaella Meazza, Matteo Capaia, Marina Fabbi, Bruno Azzarone, Enrico Balleari, Marco Gobbi, Giovanna Cutrona, Manlio Ferrarini, Silvano Ferrini

  Source: Blood. 2008 Jan 15

  View Full Text

• Interleukin-21 receptor (IL-21R) is up-regulated by CD40 triggering and mediates proapoptotic signals in chronic lymphocytic leukemia B cells.

  Interleukin-21 (IL-21) is a member of the IL-2 cytokine family, which mediates proliferation or growth arrest and apoptosis of normal B cells, dependi…

  Authors: Daniela de Totero, Raffaella Meazza, Simona Zupo, Giovanna Cutrona, Serena Matis, Monica Colombo, Enrico Balleari, Ivana Pierri, Marina Fabbi, Matteo Capaia,…

  Source: Blood. 2006 May 1

  View Full Text

• A multicenter, randomized clinical trial comparing zoledronic acid versus observation in patients with asymptomatic myeloma.

  BACKGROUND: Bisphosphonates (BPs) are effective in the prevention and treatment of skeletal-related events (SREs) in patients with symptomatic myeloma…

  Authors: Pellegrino Musto, Maria Teresa Petrucci, Sara Bringhen, Tommasina Guglielmelli, Tommaso Caravita, Velia Bongarzoni, Alessandro Andriani, Giovanni D'Arena, Enrico Balleari, Giuseppe Pietrantuono,…

  Source: Cancer. 2008 Oct 1

  View Full Text

• Purpura as the initial presentation for small-cell lung cancer.

  BACKGROUND: Causes of thrombocytopenia (TP) in patients affected by small-cell lung cancer (SCLC) include myelophtysis, immunomediated TP, disseminate…

  Authors: Gabriele Zoppoli, Enrico Balleari, Andrea Bruzzone, Luca Mastracci, Riccardo Ghio

  Source: Onkologie. 2009 May

  View Full Text

• Unusual myeloma relapse after thalidomide therapy: the dark side of the moon?

  Authors: Enrico Balleari, Andrea Bruzzone

  Source: Leukemia research. 2009 Sep

  View Full Text

• Adding low-dose gemtuzumab ozogamicin to fludarabine, Ara-C and idarubicin (MY-FLAI) may improve disease-free and overall survival in elderly patients with non-M3 acute myeloid leukaemia: results of a prospective, pilot, multi-centre trial and comparison with a historical cohort of patients.

  We report the final results of a prospective multi-centre trial testing the combination of chemotherapy (fludarabine, cytosine arabinoside and idarubi…

  Authors: Marino Clavio, Luana Vignolo, Alessandra Albarello, Riccardo Varaldo, Ivana Pierri, Gioacchino Catania, Manuela Balocco, Gianluca Michelis, Maurizio Miglino, Annunziata Manna,…

  Source: British journal of haematology. 2007 Jul

  View Full Text

• Seventeen years of experience with ATRA-based therapy for acute promyelocytic leukaemia: long-term follow-up of patients treated at S. Martino Hospital, Genoa.

  We conducted a long-term follow-up retrospective study on 91 consecutive newly diagnosed acute promyelocytic leukaemia (APL) patients. Induction and c…

  Authors: Marino Clavio, Anna Ghiso, Chiara Ghiggi, Mauro Spriano, Nicoletta Colombo, Raffaella Grasso, Riccardo Varaldo, Maurizio Miglino, Ivana Pierri, Francesca Olcese,…

  Source: Oncology reports. 2009 Apr

  View Full Text

• Darbepoetin alpha for the treatment of anaemia in low-intermediate risk myelodysplastic syndromes.

  Thirty-seven anaemic subjects with low-to-intermediate risk myelodysplastic syndrome (MDS) received the highly glycosylated, long-acting erythropoiesi…

  Authors: Pellegrino Musto, Francesco Lanza, Enrico Balleari, Alberto Grossi, Antonietta Falcone, Grazia Sanpaolo, Carlo Bodenizza, Potito Rosario Scalzulli, Antonio La Sala, Diana Campioni,…

  Source: British journal of haematology. 2005 Jan

  View Full Text

• The addition of radiotherapy to chemotherapy does not improve outcome of early stage Hodgkin's lymphoma patients: a retrospective long-term follow-up analysis of a regional Italian experience.

  We retrospectively reviewed 139 stage I-II HL patients who were diagnosed and followed up in an Italian northern region (Liguria) from 1995 to 2007, a…

  Authors: Francesca Olcese, Marino Clavio, Edoardo Rossi, Mauro Spriano, Filippo Ballerini, Letizia Canepa, Ivana Pierri, Sara Aquino, Riccardo Varaldo, Annunziata Manna,…

  Source: Annals of hematology. 2009 Sep

  View Full Text

• CD40 triggering enhances fludarabine-induced apoptosis of chronic lymphocytic leukemia B-cells through autocrine release of tumor necrosis factor-alpha and interferon-gama and tumor necrosis factor receptor-I-II upregulation.

  BACKGROUND AND OBJECTIVES: In chronic lymphocytic leukemia (CLL) B-cells are refractory to activation signals and to apoptosis. CD40 triggering, howev…

  Authors: Daniela de Totero, P L Tazzari, Matteo Capaia, Maria Pina Montera, Marino Clavio, Enrico Balleari, Robin Foa, Marco Gobbi

  Source: Haematologica. 2003 Feb

  View Full Text