1 to 10 of 14 literature results

• Large recurrent microdeletions associated with schizophrenia.

  Reduced fecundity, associated with severe mental disorders, places negative selection pressure on risk alleles and may explain, in part, why common va…

  Authors: Hreinn Stefansson, Dan Rujescu, Sven Cichon, Olli P H Pietiläinen, Andres Ingason, Stacy Steinberg, Ragnheidur Fossdal, Engilbert Sigurdsson, Thordur Sigmundsson, Jacobine E Buizer-Voskamp,…

  Source: Nature. 2008 Sep 11

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• Common variants conferring risk of schizophrenia.

  Schizophrenia is a complex disorder, caused by both genetic and environmental factors and their interactions. Research on pathogenesis has traditional…

  Authors: Hreinn Stefansson, Roel A Ophoff, Stacy Steinberg, Ole A Andreassen, Sven Cichon, Dan Rujescu, Thomas Werge, Olli P H Pietiläinen, Ole Mors, Preben B Mortensen,…

  Source: Nature. 2009 Aug 6

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• Catechol-O-methyltransferase Val 158 Met polymorphism and antisaccade eye movements in schizophrenia.

  The catechol-O-methyltransferase (COMT) enzyme catabolizes dopamine. The val(158)met single nucleotide polymorphism (rs4680) in the COMT gene has rece…

  Authors: Haraldur Magnus Haraldsson, Ulrich Ettinger, Brynja B Magnusdottir, Thordur Sigmundsson, Engilbert Sigurdsson, Andres Ingason, Hannes Petursson

  Source: Schizophrenia bulletin. 2010 Jan

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• Neuregulin-1 genotypes and eye movements in schizophrenia.

  Neuregulin-1 (NRG-1) is a putative susceptibility gene for schizophrenia but the neurocognitive processes that may involve NRG-1 in schizophrenia are …

  Authors: H Magnus Haraldsson, Ulrich Ettinger, Brynja B Magnusdottir, Andres Ingason, Samuel B Hutton, Thordur Sigmundsson, Engilbert Sigurdsson, Hannes Petursson

  Source: European archives of psychiatry and clinical neuroscience. 2010 Feb

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• Eye movement deficits in schizophrenia: investigation of a genetically homogenous Icelandic sample.

  BACKGROUND: Deficits in antisaccade (AS) and smooth pursuit eye movements (SPEM) are promising endophenotypes in genetic studies of schizophrenia. The…

  Authors: H Magnus Haraldsson, Ulrich Ettinger, Brynja B Magnusdottir, Thordur Sigmundsson, Engilbert Sigurdsson, Hannes Petursson

  Source: European archives of psychiatry and clinical neuroscience. 2008 Sep

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• Disruption of the neurexin 1 gene is associated with schizophrenia.

  Deletions within the neurexin 1 gene (NRXN1; 2p16.3) are associated with autism and have also been reported in two families with schizophrenia. We exa…

  Authors: Dan Rujescu, Andres Ingason, Sven Cichon, Olli P H Pietiläinen, Michael R Barnes, Timothea Toulopoulou, Marco Picchioni, Evangelos Vassos, Ulrich Ettinger, Elvira Bramon,…

  Source: Human molecular genetics. 2009 Mar 1

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• COMT val(158)met genotype and smooth pursuit eye movements in schizophrenia.

  The association between the catechol-O-methyltransferase (COMT) val(158)met polymorphism (rs4680) and smooth pursuit eye movements (SPEM) was investig…

  Authors: H Magnus Haraldsson, Ulrich Ettinger, Brynja B Magnusdottir, Thordur Sigmundsson, Engilbert Sigurdsson, Andres Ingason, Hannes Petursson

  Source: Psychiatry research. 2009 Sep 30

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• Scientific articles in the Icelandic Medical Journal 2004-2008: an overview

  INTRODUCTION: In the past 5 years the Icelandic Medical Journal has undergone many changes during a period of flourishing research in Iceland. The pro…

  Authors: Tómas Gudbjartsson, Engilbert Sigurdsson

  Source: Læknablađiđ. 2009 Oct

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• Neuregulin 1 and susceptibility to schizophrenia.

  The cause of schizophrenia is unknown, but it has a significant genetic component. Pharmacologic studies, studies of gene expression in man, and studi…

  Authors: Hreinn Stefansson, Engilbert Sigurdsson, Valgerdur Steinthorsdottir, Soley Bjornsdottir, Thordur Sigmundsson, Shyamali Ghosh, Jon Brynjolfsson, Steinunn Gunnarsdottir, Omar Ivarsson, Thomas T Chou,…

  Source: American journal of human genetics. 2002 Oct

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• Public views on antidepressant treatment: lessons from a national survey.

  In Iceland, antidepressant sales figures rose from 8 Defined Daily Doses (DDD) per 1000 subjects in 1975 to 95 DDD/1000 in 2005. The aim of the study …

  Authors: Engilbert Sigurdsson, Thórdís Olafsdóttir, Magnús Gottfredsson

  Source: Nordic journal of psychiatry. 2008

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