1 to 5 of 5 literature results

• Shouts, whispers and the kiss of death: directional secretion in T cells.

  T cells use secreted soluble factors for highly specific intercellular communication and targeted cell killing. This specificity is achieved first thr…

  Authors: Morgan Huse, Emily J Quann, Mark M Davis

  Source: Nature immunology. 2008 Oct

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• Localized diacylglycerol drives the polarization of the microtubule-organizing center in T cells.

  The reorientation of the T cell microtubule-organizing center (MTOC) toward the antigen-presenting cell enables the directional secretion of cytokines…

  Authors: Emily J Quann, Ernesto Merino, Toshiaki Furuta, Morgan Huse

  Source: Nature immunology. 2009 Jun

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• The p38 MAPK pathway mediates aryl propionic acid induced messenger rna stability of p75 NTR in prostate cancer cells.

  The p75(NTR) acts as a tumor suppressor in the prostate, but its expression is lost as prostate cancer progresses and is minimal in established prosta…

  Authors: Emily J Quann, Fatima Khwaja, Daniel Djakiew

  Source: Cancer research. 2007 Dec 1

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• The aryl propionic acid R-flurbiprofen selectively induces p75NTR-dependent decreased survival of prostate tumor cells.

  Epidemiologic studies show that patients chronically consuming nonsteroidal anti-inflammatory drugs (NSAID) for arthritis exhibit a reduced incidence …

  Authors: Emily J Quann, Fatima Khwaja, Kenton H Zavitz, Daniel Djakiew

  Source: Cancer research. 2007 Apr 1

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• Carprofen induction of p75NTR-dependent apoptosis via the p38 mitogen-activated protein kinase pathway in prostate cancer cells.

  The p75 neurotrophin receptor (p75(NTR)) functions as a tumor suppressor in prostate epithelial cells, where its expression declines with progression …

  Authors: Fatima S Khwaja, Emily J Quann, Nagarajan Pattabiraman, Shehla Wynne, Daniel Djakiew

  Source: Molecular cancer therapeutics. 2008 Nov

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