1 to 10 of 33 literature results

• REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis.

  We conducted a genome-wide association study of rheumatoid arthritis in 2,418 cases and 4,504 controls from North America and identified an associatio…

  Authors: Peter K Gregersen, Chistopher I Amos, Annette T Lee, Yue Lu, Elaine F Remmers, Daniel L Kastner, Michael F Seldin, Lindsey A Criswell, Robert M Plenge, V Michael Holers,…

  Source: Nature genetics. 2009 Jul

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• Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk.

  To discover new rheumatoid arthritis (RA) risk loci, we systematically examined 370 SNPs from 179 independent loci with P < 0.001 in a published meta-…

  Authors: Soumya Raychaudhuri, Brian P Thomson, Elaine F Remmers, Stephen Eyre, Anne Hinks, Candace Guiducci, Joseph J Catanese, Gang Xie, Eli A Stahl, Robert Chen,…

  Source: Nature genetics. 2009 Dec

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• Genetic risk factors for rheumatoid arthritis differ in Caucasian and Korean populations.

  OBJECTIVE: Recent studies have identified a number of novel rheumatoid arthritis (RA) susceptibility loci in Caucasian populations. The aim of this st…

  Authors: Hye-Soon Lee, Benjamin D Korman, Julie M Le, Daniel L Kastner, Elaine F Remmers, Peter K Gregersen, Sang-Cheol Bae

  Source: Arthritis and rheumatism. 2009 Feb

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• The chromosome 7q region association with rheumatoid arthritis in females in a British population is not replicated in a North American case-control series.

  OBJECTIVE: The single-nucleotide polymorphism (SNP) rs11761231 on chromosome 7q has been reported to be sexually dimorphic marker for rheumatoid arthr…

  Authors: Benjamin D Korman, Michael F Seldin, Kimberly E Taylor, Julie M Le, Annette T Lee, Robert M Plenge, Christopher I Amos, Lindsey A Criswell, Peter K Gregersen, Daniel L Kastner,…

  Source: Arthritis and rheumatism. 2009 Jan

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• Common variants at CD40 and other loci confer risk of rheumatoid arthritis.

  To identify rheumatoid arthritis risk loci in European populations, we conducted a meta-analysis of two published genome-wide association (GWA) studie…

  Authors: Soumya Raychaudhuri, Elaine F Remmers, Annette T Lee, Rachel Hackett, Candace Guiducci, Noël P Burtt, Lauren Gianniny, Benjamin D Korman, Leonid Padyukov, Fina A S Kurreeman,…

  Source: Nature genetics. 2008 Oct

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• Two independent alleles at 6q23 associated with risk of rheumatoid arthritis.

  To identify susceptibility alleles associated with rheumatoid arthritis, we genotyped 397 individuals with rheumatoid arthritis for 116,204 SNPs and c…

  Authors: Robert M Plenge, Chris Cotsapas, Leela Davies, Alkes L Price, Paul I W de Bakker, Julian Maller, Itsik Pe'er, Noel P Burtt, Brendan Blumenstiel, Matt DeFelice,…

  Source: Nature genetics. 2007 Dec

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• Familial Mediterranean fever with a single MEFV mutation: where is the second hit?

  OBJECTIVE: Familial Mediterranean fever (FMF) has traditionally been considered an autosomal-recessive disease; however, it has been observed that a s…

  Authors: Matthew G Booty, Jae Jin Chae, Seth L Masters, Elaine F Remmers, Beverly Barham, Julie M Le, Karyl S Barron, Steve M Holland, Daniel L Kastner, Ivona Aksentijevich

  Source: Arthritis and rheumatism. 2009 Jun

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• Functional phosphodiesterase 11A mutations may modify the risk of familial and bilateral testicular germ cell tumors.

  Inactivating germline mutations in phosphodiesterase 11A (PDE11A) have been implicated in adrenal tumor susceptibility. PDE11A is highly expressed in …

  Authors: Anelia Horvath, Larissa Korde, Mark H Greene, Rossella Libe, Paulo Osorio, Fabio Rueda Faucz, Marie Laure Raffin-Sanson, Kit Man Tsang, Limor Drori-Herishanu, Yianna Patronas,…

  Source: Cancer research. 2009 Jul 1

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• Replication of putative candidate-gene associations with rheumatoid arthritis in >4,000 samples from North America and Sweden: association of susceptibility with PTPN22, CTLA4, and PADI4.

  Candidate-gene association studies in rheumatoid arthritis (RA) have lead to encouraging yet apparently inconsistent results. One explanation for the …

  Authors: Robert M Plenge, Leonid Padyukov, Elaine F Remmers, Shaun Purcell, Annette T Lee, Elizabeth W Karlson, Frederick Wolfe, Daniel L Kastner, Lars Alfredsson, David Altshuler,…

  Source: American journal of human genetics. 2005 Dec

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• The clinical continuum of cryopyrinopathies: novel CIAS1 mutations in North American patients and a new cryopyrin model.

  OBJECTIVE: The cryopyrinopathies are a group of rare autoinflammatory disorders that are caused by mutations in CIAS1, encoding the cryopyrin protein.…

  Authors: Ivona Aksentijevich, Christopher D Putnam, Elaine F Remmers, James L Mueller, Julie Le, Richard D Kolodner, Zachary Moak, Michael Chuang, Frances Austin, Raphaela Goldbach-Mansky,…

  Source: Arthritis and rheumatism. 2007 Apr

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