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Coordinated regulation of nutrient and inflammatory responses by STAMP2 is essential for metabolic homeostasis.
Metabolic and inflammatory pathways crosstalk at many levels, and, while required for homeostasis, interaction between these pathways can also lead to…
Authors: Kathryn E Wellen, Raquel Fucho, Margaret F Gregor, Masato Furuhashi, Carlos Morgan, Torstein Lindstad, Eric Vaillancourt, Cem Z Gorgun, Fahri Saatcioglu, Gökhan S Hotamisligil
Source: Cell. 2007 May 4
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Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2.
Adipocyte fatty-acid-binding protein, aP2 (FABP4) is expressed in adipocytes and macrophages, and integrates inflammatory and metabolic responses. Stu…
Authors: Masato Furuhashi, Gürol Tuncman, Cem Z Görgün, Liza Makowski, Genichi Atsumi, Eric Vaillancourt, Keita Kono, Vladimir R Babaev, Sergio Fazio, MacRae F Linton,…
Source: Nature. 2007 Jun 21
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Predicting grip force amplitude involves circuits in the anterior basal ganglia.
The ability to grip objects allows us to perform many activities of daily living such as eating and drinking. Lesions to and disorders of the basal ga…
Authors: Pooja Wasson, Janey Prodoehl, Stephen A Coombes, Daniel M Corcos, David E Vaillancourt
Source: NeuroImage. 2010 Feb 15
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Basal ganglia mechanisms underlying precision grip force control.
The classic grasping network has been well studied but thus far the focus has been on cortical regions in the control of grasping. Sub-cortically, spe…
Authors: Janey Prodoehl, Daniel M Corcos, David E Vaillancourt
Source: Neuroscience and biobehavioral reviews. 2009 Jun
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Region of interest template for the human basal ganglia: comparing EPI and standardized space approaches.
Identifying task-related activation in the basal ganglia (BG) is an important area of interest in normal motor systems and cognitive neuroscience. The…
Authors: Janey Prodoehl, Hong Yu, Deborah M Little, Ivy Abraham, David E Vaillancourt
Source: NeuroImage. 2008 Feb 1
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Few Mendelian genes underlie the quantitative response of a forest tree, Eucalyptus globulus, to a natural fungal epidemic.
Foliar fungal pathogens from the genus Mycosphaerella affect eucalyptus in natural forests and plantations worldwide. QTL analysis was conducted to di…
Authors: Jules S Freeman, Brad M Potts, René E Vaillancourt
Source: Genetics. 2008 Jan
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Role of hyperactive cerebellum and motor cortex in Parkinson's disease.
Previous neuroimaging studies have found hyperactivation in the cerebellum and motor cortex and hypoactivation in the basal ganglia in patients with P…
Authors: Hong Yu, Dagmar Sternad, Daniel M Corcos, David E Vaillancourt
Source: NeuroImage. 2007 Mar
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High-resolution diffusion tensor imaging in the substantia nigra of de novo Parkinson disease.
BACKGROUND: In the midbrain of patients with Parkinson disease (PD), there is a selective loss of dopaminergic neurons in the ventrolateral and caudal…
Authors: D E Vaillancourt, M B Spraker, J Prodoehl, I Abraham, D M Corcos, X J Zhou, C L Comella, D M Little
Source: Neurology. 2009 Apr 21
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Role of the basal ganglia and frontal cortex in selecting and producing internally guided force pulses.
The basal ganglia comprise a crucial circuit involved in force production and force selection, but the specific role of each nucleus to the production…
Authors: David E Vaillancourt, Hong Yu, Mary A Mayka, Daniel M Corcos
Source: NeuroImage. 2007 Jul 1
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Three-dimensional locations and boundaries of motor and premotor cortices as defined by functional brain imaging: a meta-analysis.
The mesial premotor cortex (pre-supplementary motor area and supplementary motor area proper), lateral premotor cortex (dorsal premotor cortex and ven…
Authors: Mary A Mayka, Daniel M Corcos, Sue E Leurgans, David E Vaillancourt
Source: NeuroImage. 2006 Jul 15
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