1 to 10 of 15 literature results

• Methylation of histone H3R2 by PRMT6 and H3K4 by an MLL complex are mutually exclusive.

  Eukaryotic genomes are organized into active (euchromatic) and inactive (heterochromatic) chromatin domains. Post-translational modifications of histo…

  Authors: Ernesto Guccione, Christian Bassi, Fabio Casadio, Francesca Martinato, Matteo Cesaroni, Henning Schuchlautz, Bernhard Lüscher, Bruno Amati

  Source: Nature. 2007 Oct 18

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• Myc-binding-site recognition in the human genome is determined by chromatin context.

  Large-scale chromatin immunoprecipitation (ChIP) studies have been effective in unravelling the distribution of DNA-binding transcription factors alon…

  Authors: Ernesto Guccione, Francesca Martinato, Giacomo Finocchiaro, Lucilla Luzi, Laura Tizzoni, Valentina Dall' Olio, Giuseppe Zardo, Clara Nervi, Loris Bernard, Bruno Amati

  Source: Nature cell biology. 2006 Jul

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• A positive role for Myc in TGFbeta-induced Snail transcription and epithelial-to-mesenchymal transition.

  Myc and transforming growth factor-beta (TGFbeta) signaling are mutually antagonistic, that is Myc suppresses the activation of TGFbeta-induced genes,…

  Authors: A P Smith, A Verrecchia, G Fagà, M Doni, D Perna, F Martinato, E Guccione, B Amati

  Source: Oncogene. 2009 Jan 22

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• Amino acid-dependent growth of Campylobacter jejuni: key roles for aspartase (AspA) under microaerobic and oxygen-limited conditions and identification of AspB (Cj0762), essential for growth on glutamate.

  Amino acids are key carbon and energy sources for the asaccharolytic food-borne human pathogen Campylobacter jejuni. During microaerobic growth in ami…

  Authors: Edward Guccione, Maria del Rocio Leon-Kempis, Bruce M Pearson, Edward Hitchin, Francis Mulholland, Pauline M van Diemen, Mark P Stevens, David J Kelly

  Source: Molecular microbiology. 2008 Jul

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• The Campylobacter jejuni PEB1a adhesin is an aspartate/glutamate-binding protein of an ABC transporter essential for microaerobic growth on dicarboxylic amino acids.

  The PEB1a protein of the gastrointestinal pathogen Campylobacter jejuni mediates interactions with epithelial cells and is an important factor in host…

  Authors: Maria del Rocio Leon-Kempis, Edward Guccione, Francis Mulholland, Michael P Williamson, David J Kelly

  Source: Molecular microbiology. 2006 Jun

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• HPV E6 proteins interact with specific PML isoforms and allow distinctions to be made between different POD structures.

  Mucosal human papillomaviruses (HPVs) are the causative agents of a number of human pathologies, including benign condylomas, as well as of the majori…

  Authors: Ernesto Guccione, Katherine J Lethbridge, Neil Killick, Keith N Leppard, Lawrence Banks

  Source: Oncogene. 2004 Jun 10

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• The Ankrd2 protein, a link between the sarcomere and the nucleus in skeletal muscle.

  Ankrd2 may be a link between the sarcomere and the nucleus; a similar role has recently been proposed for CARP that has a high level of structural and…

  Authors: Snezana Kojic, Elisa Medeot, Ernesto Guccione, Helena Krmac, Ivano Zara, Valentina Martinelli, Giorgio Valle, Georgine Faulkner

  Source: Journal of molecular biology. 2004 May 28

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• Oncogenic human papillomavirus E6 proteins target the MAGI-2 and MAGI-3 proteins for degradation.

  The E6 proteins from the high-risk human papillomavirus (HPV) types have previously been shown to target a number of PDZ domain-containing proteins fo…

  Authors: Miranda Thomas, Richard Laura, Karin Hepner, Ernesto Guccione, Charles Sawyers, Laurence Lasky, Lawrence Banks

  Source: Oncogene. 2002 Aug 1

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• Comparative analysis of the intracellular location of the high- and low-risk human papillomavirus oncoproteins.

  We have compared the intracellular location of the HPV E6 and E7 proteins from high- and low-risk virus types. While high-risk HPV E7 displays diffuse…

  Authors: Ernesto Guccione, Paola Massimi, Agnieszka Bernat, Lawrence Banks

  Source: Virology. 2002 Feb 1

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• Nucleotide sequence, transcription map, and mutation analysis of the 13q14 chromosomal region deleted in B-cell chronic lymphocytic leukemia.

  Deletions of the 13q14 chromosome region are associated with B-cell chronic lymphocytic leukemia (B-CLL) and several other types of cancer, suggesting…

  Authors: A Migliazza, F Bosch, H Komatsu, E Cayanis, S Martinotti, E Toniato, E Guccione, X Qu, M Chien, V V Murty,…

  Source: Blood. 2001 Apr 1

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