1 to 10 of 17 literature results

• Distinctive localization of antigen-presenting cells in human lymph nodes.

  Professional antigen-presenting cells (APCs) are sentinel cells of the immune system that present antigen to T lymphocytes and mediate an appropriate …

  Authors: Catherine E Angel, Chun-Jen J Chen, Oliver C Horlacher, Sintia Winkler, Thomas John, Judy Browning, Duncan MacGregor, Jonathan Cebon, P Rod Dunbar

  Source: Blood. 2009 Feb 5

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• The regulatory T cell-associated transcription factor FoxP3 is expressed by tumor cells.

  FoxP3 is a member of the forkhead family of transcription factors critically involved in the development and function of CD25(+) regulatory T cells (T…

  Authors: Lisa M Ebert, Bee Shin Tan, Judy Browning, Suzanne Svobodova, Sarah E Russell, Naomi Kirkpatrick, Craig Gedye, Denis Moss, Sweet Ping Ng, Duncan MacGregor,…

  Source: Cancer research. 2008 Apr 15

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• Desmoplastic melanoma: comparison of expression of differentiation antigens and cancer testis antigens.

  Desmoplastic melanoma is a diagnostic and therapeutic challenge. Immunohistochemical analysis with antibodies to melanoma antigens can complement morp…

  Authors: Elgene Lim, Judy Browning, Duncan MacGregor, Ian D Davis, Jonathan S Cebon

  Source: Melanoma research. 2006 Aug

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• The risks of thin basement membrane nephropathy.

  Most individuals with thin basement membrane nephropathy (TBMN) have an excellent prognosis. For these patients, the only hazards are the anxiety rela…

  Authors: Stephen Tonna, Yan Yan Wang, Duncan MacGregor, Roger Sinclair, Paul Martinello, David Power, Judy Savige

  Source: Seminars in nephrology. 2005 May

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• Perforin-mediated suppression of B-cell lymphoma.

  In the present study, we have examined the effect of perforin (pfp) deficiency in 4 models of mouse B-cell lymphomagenesis. We have examined pfp loss …

  Authors: Paul Bolitho, Shayna E A Street, Jennifer A Westwood, Winfried Edelmann, Duncan Macgregor, Paul Waring, William K Murray, Dale I Godfrey, Joseph A Trapani, Ricky W Johnstone,…

  Source: Proceedings of the National Academy of Sciences of the United States of America. 2009 Feb 24

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• Tumor antigen expression in melanoma varies according to antigen and stage.

  PURPOSE: Melanoma cells express antigens that can induce T-cell and antibody responses. Obtaining a detailed understanding of antigen expression in pr…

  Authors: Catherine Barrow, Judy Browning, Duncan MacGregor, Ian D Davis, Sue Sturrock, Achim A Jungbluth, Jonathan Cebon

  Source: Clinical cancer research : an official journal of the American Association for Cancer Research. 2006 Feb 1

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• A phase I biodistribution and pharmacokinetic trial of humanized monoclonal antibody Hu3s193 in patients with advanced epithelial cancers that express the Lewis-Y antigen.

  PURPOSE: We report a first-in-man trial of a humanized antibody (hu3S193) against the Le(y) antigen. EXPERIMENTAL DESIGN: Patients with advanced Le(y)…

  Authors: Andrew M Scott, Niall Tebbutt, Fook-Thean Lee, Tina Cavicchiolo, Zhanqi Liu, Sanjeev Gill, Aurora M T Poon, Wendie Hopkins, Fiona E Smyth, Carmel Murone,…

  Source: Clinical cancer research : an official journal of the American Association for Cancer Research. 2007 Jun 1

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• A phase I clinical trial with monoclonal antibody ch806 targeting transitional state and mutant epidermal growth factor receptors.

  An array of cell-surface antigens expressed by human cancers have been identified as targets for antibody-based therapies. The great majority of these…

  Authors: Andrew M Scott, Fook-Thean Lee, Niall Tebbutt, Rebecca Herbertson, Sanjeev S Gill, Zhanqi Liu, Effie Skrinos, Carmel Murone, Timothy H Saunder, Bridget Chappell,…

  Source: Proceedings of the National Academy of Sciences of the United States of America. 2007 Mar 6

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• Suppression of lymphoma and epithelial malignancies effected by interferon gamma.

  The immunosurveillance of transformed cells by the immune system remains one of the most controversial and poorly understood areas of immunity. Gene-t…

  Authors: Shayna E A Street, Joseph A Trapani, Duncan MacGregor, Mark J Smyth

  Source: The Journal of experimental medicine. 2002 Jul 1

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• Characterization of antigen-specific CD8+ T lymphocyte responses in skin and peripheral blood following intradermal peptide vaccination.

  Immune responses to cancer vaccines are commonly tested by measuring cutaneous reactions to intradermal (i.d.) antigen. When well-characterized peptid…

  Authors: Qiyuan Chen, Heather Jackson, Mark Shackleton, Phillip Parente, Wendie Hopkins, Sue Sturrock, Duncan MacGregor, Eugene Maraskovsky, Tsin Yee Tai, Nektaria Dimopoulos,…

  Source: Cancer immunity : a journal of the Academy of Cancer Immunology. 2005 Mar 9

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