1 to 10 of 25 literature results

• Support for neuregulin 1 as a susceptibility gene for bipolar disorder and schizophrenia.

  BACKGROUND: There is support that Neuregulin 1 (NRG1) plays a role in susceptibility to schizophrenia but limited evidence for its involvement in bipo…

  Authors: Lyudmila Georgieva, Albena Dimitrova, Dobril Ivanov, Ivan Nikolov, Nigel M Williams, Detelina Grozeva, Irina Zaharieva, Draga Toncheva, Michael J Owen, George Kirov,…

  Source: Biological psychiatry. 2008 Sep 1

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• Case-control association study of 65 candidate genes revealed a possible association of a SNP of HTR5A to be a factor susceptible to bipolar disease in Bulgarian population.

  BACKGROUND: Bipolar affective disorder (BAD) is a psychiatric illness characterized by episodes of mania and depression. Although the etiology is not …

  Authors: Adelina Yosifova, Taisei Mushiroda, Drozdstoi Stoianov, Radoslava Vazharova, Ivanka Dimova, Sena Karachanak, Irina Zaharieva, Vihra Milanova, Nadejda Madjirova, Ivan Gerdjikov,…

  Source: Journal of affective disorders. 2009 Sep

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• Coexistence of copy number increases of c-Myc, ZNF217, CCND1, ErbB1 and ErbB2 in ovarian cancers.

  BACKGROUND: We selected 5 oncogenes with well-established roles in carcinogenesis -- CCND1, ErbB1, ErbB2, c-myc and ZNF217 -- to investigate the coexi…

  Authors: Ivanka Dimova, Sashka Raicheva, Rumen Dimitrov, Nikolai Doganov, Draga Toncheva

  Source: Onkologie. 2009 Jul

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• Increased C-MYC copy numbers on the background of CDKN2A loss is associated with improved survival in nodular melanoma.

  PURPOSE: In order to obtain better insight into the genetic background of nodular melanoma (NM), we aimed to analyse the frequency of CDKN2A and C-MYC…

  Authors: Denitsa Koynova, Ekaterina Jordanova, Nicole Kukutsch, Pieter van der Velden, Draga Toncheva, Nelleke Gruis

  Source: Journal of cancer research and clinical oncology. 2007 Feb

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• No association between MDR1 (ABCB1) 2677G>T and 3435C>T polymorphism and sporadic colorectal cancer among Bulgarian patients.

  PURPOSE: Variation in genetic factors together with xenobiotic exposure may result in increased risk of colorectal cancer. The P-glycoprotein (P-gp) i…

  Authors: Darinka Todorova Petrova, Petya Nedeva, Svilen Maslyankov, Svetoslav Toshev, Nikolay Yaramov, Srebrena Atanasova, Draga Toncheva, Michael Oellerich, Nicolas von Ahsen

  Source: Journal of cancer research and clinical oncology. 2008 Mar

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• Strong evidence for association between the dystrobrevin binding protein 1 gene (DTNBP1) and schizophrenia in 488 parent-offspring trios from Bulgaria.

  BACKGROUND: The gene encoding the dystrobrevin binding protein (DTNBP1) has been implicated in the pathogenesis of schizophrenia by several associatio…

  Authors: George Kirov, Dobril Ivanov, Nigel M Williams, Anna Preece, Ivan Nikolov, Radoi Milev, Svetlinka Koleva, Albena Dimitrova, Draga Toncheva, Michael C O'Donovan,…

  Source: Biological psychiatry. 2004 May 15

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• Fifty years of Balkan endemic nephropathy: challenges of study using epidemiological method.

  Balkan endemic nephropathy (BEN) is a chronic tubulointerstitial disease associated with urothelial cancer, which affects people living in the alluvia…

  Authors: Vladisav Stefanovic, Rade Cukuranovic, Sladjana Miljkovic, Dragoslav Marinkovic, Draga Toncheva

  Source: Renal failure. 2009

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• Expression of chloride intracellular channel protein 1 (CLIC1) and tumor protein D52 (TPD52) as potential biomarkers for colorectal cancer.

  OBJECTIVES: Unequivocal biomarkers are needed to predict susceptibility and progression of colorectal cancer. DESIGN AND METHODS: Paired samples of tu…

  Authors: Darinka Todorova Petrova, Abdul R Asif, Victor W Armstrong, Ivanka Dimova, Svetoslav Toshev, Nikolay Yaramov, Michael Oellerich, Draga Toncheva

  Source: Clinical biochemistry. 2008 Oct

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• Urinary neopterin concentrations in patients with Balkan endemic nephropathy (BEN).

  BACKGROUND: Balkan endemic nephropathy (BEN) is of great clinical importance in restricted areas of Bulgaria, Serbia, Croatia, Bosnia, Herzegovina, an…

  Authors: Draga Toncheva, Angel S Galabov, Andreas Laich, Srebrena Atanassova, Bojin Kamarinchev, Tzvetan Dimitrov, Dietmar Fuchs

  Source: Kidney international. 2003 Nov

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• Genome-wide gene expression profiles of thyroid carcinoma: Identification of molecular targets for treatment of thyroid carcinoma.

  In order to clarify the molecular mechanism involved in thyroid carcinogenesis and to identify candidate molecular targets for diagnosis and treatment…

  Authors: Dragomira Nikolaeva Nikolova, Hitoshi Zembutsu, Tanio Sechanov, Kalin Vidinov, Low Siew Kee, Radina Ivanova, Elitza Becheva, Miriana Kocova, Draga Toncheva, Yusuke Nakamura

  Source: Oncology reports. 2008 Jul

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