1 to 6 of 6 literature results

• Support for the involvement of large copy number variants in the pathogenesis of schizophrenia.

  We investigated the involvement of rare (<1%) copy number variants (CNVs) in 471 cases of schizophrenia and 2792 controls that had been genotyped usin…

  Authors: George Kirov, Detelina Grozeva, Nadine Norton, Dobril Ivanov, Kiran K Mantripragada, Peter Holmans, International Schizophrenia Consortium, Wellcome Trust Case Control Consortium, Nick Craddock, Michael J Owen,…

  Source: Human molecular genetics. 2009 Apr 15

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• A meta-analysis of nonsense mutations causing human genetic disease.

  Nonsense mutations account for approximately 11% of all described gene lesions causing human inherited disease and approximately 20% of disease-associ…

  Authors: Matthew Mort, Dobril Ivanov, David N Cooper, Nadia A Chuzhanova

  Source: Human mutation. 2008 Aug

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• Support for neuregulin 1 as a susceptibility gene for bipolar disorder and schizophrenia.

  BACKGROUND: There is support that Neuregulin 1 (NRG1) plays a role in susceptibility to schizophrenia but limited evidence for its involvement in bipo…

  Authors: Lyudmila Georgieva, Albena Dimitrova, Dobril Ivanov, Ivan Nikolov, Nigel M Williams, Detelina Grozeva, Irina Zaharieva, Draga Toncheva, Michael J Owen, George Kirov,…

  Source: Biological psychiatry. 2008 Sep 1

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• Strong evidence for association between the dystrobrevin binding protein 1 gene (DTNBP1) and schizophrenia in 488 parent-offspring trios from Bulgaria.

  BACKGROUND: The gene encoding the dystrobrevin binding protein (DTNBP1) has been implicated in the pathogenesis of schizophrenia by several associatio…

  Authors: George Kirov, Dobril Ivanov, Nigel M Williams, Anna Preece, Ivan Nikolov, Radoi Milev, Svetlinka Koleva, Albena Dimitrova, Draga Toncheva, Michael C O'Donovan,…

  Source: Biological psychiatry. 2004 May 15

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• No evidence for association between polymorphisms in GRM3 and schizophrenia.

  BACKGROUND: Three studies have previously reported data that were interpreted by the authors as supportive of association between schizophrenia and po…

  Authors: Nadine Norton, Hywel J Williams, Sarah Dwyer, Dobril Ivanov, Anna C Preece, Amy Gerrish, Nigel M Williams, Pamela Yerassimou, Stanley Zammit, Michael C O'Donovan,…

  Source: BMC psychiatry. 2005

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• Convergent evidence that oligodendrocyte lineage transcription factor 2 (OLIG2) and interacting genes influence susceptibility to schizophrenia.

  Abnormal oligodendrocyte function has been postulated as a primary etiological event in schizophrenia. Oligodendrocyte lineage transcription factor 2 …

  Authors: Lyudmila Georgieva, Valentina Moskvina, Tim Peirce, Nadine Norton, Nicholas J Bray, Lesley Jones, Peter Holmans, Stuart Macgregor, Stanley Zammit, Jennifer Wilkinson,…

  Source: Proceedings of the National Academy of Sciences of the United States of America. 2006 Aug 15

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