1 to 10 of 24 literature results

• A stem batrachian from the Early Permian of Texas and the origin of frogs and salamanders.

  The origin of extant amphibians (Lissamphibia: frogs, salamanders and caecilians) is one of the most controversial questions in vertebrate evolution, …

  Authors: Jason S Anderson, Robert R Reisz, Diane Scott, Nadia B Fröbisch, Stuart S Sumida

  Source: Nature. 2008 May 22

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• C1q enhances IFN-gamma production by antigen-specific T cells via the CD40 costimulatory pathway on dendritic cells.

  Dendritic cells (DCs) are known to produce C1q, the initiator of the classical complement pathway. We demonstrate that murine DCs deficient in C1q (C1…

  Authors: Paramita Baruah, Ingrid E Dumitriu, Talat H Malik, H Terence Cook, Julian Dyson, Diane Scott, Elizabeth Simpson, Marina Botto

  Source: Blood. 2009 Apr 9

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• Physiologic and aberrant regulation of memory T-cell trafficking by the costimulatory molecule CD28.

  Productive T-cell immunity requires both the activation and the migration of specific T cells to the antigenic tissue. The costimulatory molecule CD28…

  Authors: Vincenzo Mirenda, Sarah J Jarmin, Rachel David, Julian Dyson, Diane Scott, Yan Gu, Robert I Lechler, Klaus Okkenhaug, Federica M Marelli-Berg

  Source: Blood. 2007 Apr 1

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• OPCML at 11q25 is epigenetically inactivated and has tumor-suppressor function in epithelial ovarian cancer.

  Epithelial ovarian cancer (EOC), the leading cause of death from gynecological malignancy, is a poorly understood disease. The typically advanced pres…

  Authors: Grant C Sellar, Karen P Watt, Genevieve J Rabiasz, Euan A Stronach, Li Li, Eric P Miller, Charles E Massie, Jayne Miller, Bruno Contreras-Moreira, Diane Scott,…

  Source: Nature genetics. 2003 Jul

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• Transplantation tolerance induced by intranasal administration of HY peptides.

  Induction of antigen-specific tolerance to transplantation antigens is desirable to control host-versus-graft and graft-versus-host reactions. Followi…

  Authors: Jian-Guo Chai, Edward James, Hamlata Dewchand, Elizabeth Simpson, Diane Scott

  Source: Blood. 2004 May 15

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• Cognate recognition of the endothelium induces HY-specific CD8+ T-lymphocyte transendothelial migration (diapedesis) in vivo.

  The physiologic significance of MHC-peptide complex presentation by endothelial cells (ECs) to trafficking T lymphocytes remains unresolved. On the ba…

  Authors: Federica M Marelli-Berg, Martha J James, John Dangerfield, Julian Dyson, Maggie Millrain, Diane Scott, Elizabeth Simpson, Sussan Nourshargh, Robert I Lechler

  Source: Blood. 2004 Apr 15

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• Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide.

  Mesenchymal stem cells (MSCs) have been recently shown to inhibit T-cell proliferation to polyclonal stimuli. We characterized the effect of MSCs of b…

  Authors: Mauro Krampera, Sarah Glennie, Julian Dyson, Diane Scott, Ruthline Laylor, Elizabeth Simpson, Francesco Dazzi

  Source: Blood. 2003 May 1

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• Anergic T cells exert antigen-independent inhibition of cell-cell interactions via chemokine metabolism.

  Due to their ability to inhibit antigen-induced T-cell activation in vitro and in vivo, anergic T cells can be considered part of the spectrum of immu…

  Authors: Martha J James, Lavina Belaramani, Kanella Prodromidou, Arpita Datta, Sussan Nourshargh, Giovanna Lombardi, Julian Dyson, Diane Scott, Elizabeth Simpson, Lorraine Cardozo,…

  Source: Blood. 2003 Sep 15

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• Tolerant T cells display impaired trafficking ability.

  Based on our previous observation that anergic T lymphocytes lose their migratory ability in vitro, we have proposed that anergic T cells are retained…

  Authors: Vincenzo Mirenda, Owain Millington, Robert I Lechler, Diane Scott, Maria P Hernandez-Fuentes, Joseph Read, Peng H Tan, Andrew J T George, Paul Garside, Federica M Marelli-Berg

  Source: European journal of immunology. 2005 Jul

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• CD4+CD25+ T cells as immunoregulatory T cells in vitro.

  We have further characterized the in vitro phenotype and function of anergic and suppressive CD4(+)25(+) T cells. Following TCR ligation, DO.11.10 CD4…

  Authors: Jian-Guo Chai, Julia Y S Tsang, Robert Lechler, Elizabeth Simpson, Julian Dyson, Diane Scott

  Source: European journal of immunology. 2002 Aug

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