1 to 10 of 257 literature results

• Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers.

  Basal-like breast cancers arising in women carrying mutations in the BRCA1 gene, encoding the tumor suppressor protein BRCA1, are thought to develop f…

  Authors: Elgene Lim, François Vaillant, Di Wu, Natasha C Forrest, Bhupinder Pal, Adam H Hart, Marie-Liesse Asselin-Labat, David E Gyorki, Teresa Ward, Audrey Partanen,…

  Source: Nature medicine. 2009 Aug

  View Full Text

• Giant magnetoresistance in organic spin-valves.

  A spin valve is a layered structure of magnetic and non-magnetic (spacer) materials whose electrical resistance depends on the spin state of electrons…

  Authors: Z H Xiong, Di Wu, Z Valy Vardeny, Jing Shi

  Source: Nature. 2004 Feb 26

  View Full Text

• Crosstalk between Aurora-A and p53: frequent deletion or downregulation of Aurora-A in tumors from p53 null mice.

  The Aurora-A kinase gene is amplified in a subset of human tumors and in radiation-induced lymphomas from p53 heterozygous mice. Normal tissues from p…

  Authors: Jian-Hua Mao, Di Wu, Jesus Perez-Losada, Tao Jiang, Qian Li, Richard M Neve, Joe W Gray, Wei-Wen Cai, Allan Balmain

  Source: Cancer cell. 2007 Feb

  View Free Full Text

• Centrosome/spindle pole-associated protein regulates cytokinesis via promoting the recruitment of MyoGEF to the central spindle.

  Cooperative communications between the central spindle and the contractile ring are critical for the spatial and temporal regulation of cytokinesis. H…

  Authors: Michael Asiedu, Di Wu, Fumio Matsumura, Qize Wei

  Source: Molecular biology of the cell. 2009 Mar

  View Free Full Text

• Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene.

  The FBXW7/hCDC4 gene encodes a ubiquitin ligase implicated in the control of chromosome stability. Here we identify the mouse Fbxw7 gene as a p53-depe…

  Authors: Jian-Hua Mao, Jesus Perez-Losada, Di Wu, Reyno Delrosario, Ryosuke Tsunematsu, Keiichi I Nakayama, Ken Brown, Sheila Bryson, Allan Balmain

  Source: Nature. 2004 Dec 9

  View Full Text

• PIDD: database for Protein Inter-atomic Distance Distributions.

  Protein Inter-atomic Distance Distributions (PIDD) is a dedicated database and structural bio-informatics system for distance based protein modeling. …

  Authors: Di Wu, Feng Cui, Robert Jernigan, Zhijun Wu

  Source: Nucleic acids research. 2007 Jan

  View Full Text

• Sexual experience changes sex hormones but not hypothalamic steroid hormone receptor expression in young and middle-aged male rats.

  Testosterone is well known to regulate sexual behavior in males, but this is dependent upon prior sexual experience. Aging is associated with decrease…

  Authors: Di Wu, Andrea C Gore

  Source: Hormones and behavior. 2009 Sep

  View Full Text

• Smad2/3 activities are required for induction and patterning of the neuroectoderm in zebrafish.

  Smad2 and Smad3, two essential nuclear effectors of transforming growth factor (Tgf)-beta signals, have been found to be implicated in mesoderm and en…

  Authors: Shunji Jia, Di Wu, Cencan Xing, Anming Meng

  Source: Developmental biology. 2009 Sep 15

  View Full Text

• Mutually exclusive mutations of the Pten and ras pathways in skin tumor progression.

  Pten heterozygous (Pten+/-) mice develop increased papilloma numbers and show decreased carcinoma latency time in comparison with controls after skin …

  Authors: Jian-Hua Mao, Minh D To, Jesus Perez-Losada, Di Wu, Reyno Del Rosario, Allan Balmain

  Source: Genes & development. 2004 Aug 1

  View Free Full Text

• Gonadotropin-Releasing Hormone Neuroterminals and Their Microenvironment in the Median Eminence: Effects of Aging and Estradiol Treatment.

  The GnRH decapeptide controls reproductive function through its release from neuroendocrine terminals in the median eminence, a site where there is a …

  Authors: Weiling Yin, Di Wu, Megan L Noel, Andrea C Gore

  Source: Endocrinology. 2009 Oct 9

  View Full Text