1 to 10 of 89 literature results

• A luminal epithelial stem cell that is a cell of origin for prostate cancer.

  In epithelial tissues, the lineage relationship between normal progenitor cells and cell type(s) of origin for cancer has been poorly understood. Here…

  Authors: Xi Wang, Marianna Kruithof-de Julio, Kyriakos D Economides, David Walker, Hailong Yu, M Vivienne Halili, Ya-Ping Hu, Sandy M Price, Cory Abate-Shen, Michael M Shen

  Source: Nature. 2009 Sep 24

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• Simulation and validation of a prototype swing arm profilometer for measuring extremely large telescope mirror-segments.

  The Extremely Large Telescope (ELT) projects presuppose segmented primary mirrors. The metrology of the off-axis aspherical segments is particularly c…

  Authors: Hongwei Jing, Christopher King, David Walker

  Source: Optics express. 2010 Feb 1

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• Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections.

  CD1d-restricted natural killer T (NKT) cells are innate-like lymphocytes that express a conserved T-cell receptor and contribute to host defence again…

  Authors: Jochen Mattner, Kristin L Debord, Nahed Ismail, Randal D Goff, Carlos Cantu, Dapeng Zhou, Pierre Saint-Mezard, Vivien Wang, Ying Gao, Ning Yin,…

  Source: Nature. 2005 Mar 24

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• Exploring the use of videotaped objective structured clinical examination in the assessment of joint examination skills of medical students.

  OBJECTIVE: Objective structured clinical examination (OSCE) is a key part of medical student assessment. Currently, assessment is performed by medical…

  Authors: Pirashanthie Vivekananda-Schmidt, Martyn Lewis, David Coady, Catherine Morley, Lesley Kay, David Walker, Andrew B Hassell

  Source: Arthritis and rheumatism. 2007 Jun 15

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• Recent advances in optic nerve glioma with a focus on the young patient.

  PURPOSE OF REVIEW: Optic tract low-grade gliomas are one of the commonest category of neoplasm presenting in childhood and early adolescence. Recent r…

  Authors: David Walker

  Source: Current opinion in neurology. 2003 Dec

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• Ontogeny and nutritional programming of the hepatic growth hormone-insulin-like growth factor-prolactin axis in the sheep.

  The liver is an important metabolic and endocrine organ in the fetus, but the extent to which its hormone receptor sensitivity is developmentally regu…

  Authors: Melanie A Hyatt, Helen Budge, David Walker, Terence Stephenson, Michael E Symonds

  Source: Endocrinology. 2007 Oct

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• Are adolescents more vulnerable to drug addiction than adults? Evidence from animal models.

  BACKGROUND AND RATIONALE: Epidemiological evidence suggests that people who begin experimenting with drugs of abuse during early adolescence are more …

  Authors: Nicole L Schramm-Sapyta, Q David Walker, Joseph M Caster, Edward D Levin, Cynthia M Kuhn

  Source: Psychopharmacology. 2009 Sep

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• A single high dose of cocaine induces differential sensitization to specific behaviors across adolescence.

  RATIONALE: Adolescence is a critical period for drug addiction. Acute stimulant exposure elicits different behavioral responses in adolescent and adul…

  Authors: Joseph M Caster, Q David Walker, Cynthia M Kuhn

  Source: Psychopharmacology. 2007 Aug

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• Kynurenine pathway metabolism in human blood-brain-barrier cells: implications for immune tolerance and neurotoxicity.

  The catabolic pathway of l-tryptophan (l-trp), known as the kynurenine pathway (KP), has been implicated in the pathogenesis of a wide range of brain …

  Authors: Robert Owe-Young, Nicole L Webster, Muhammad Mukhtar, Roger J Pomerantz, George Smythe, David Walker, Patricia J Armati, Suzanne M Crowe, Bruce J Brew

  Source: Journal of neurochemistry. 2008 May

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• Exposure to treated sewage effluent disrupts reproduction and development in the seasonally breeding Ramshorn snail (subclass: Pulmonata, Planorbarius corneus).

  Experiments were conducted to assess the impacts of exposure to sewage treatment works (STW) effluent upon the growth, reproductive function, and sexu…

  Authors: Neil Clarke, Edwin J Routledge, Anthony Garner, Daire Casey, Rachel Benstead, David Walker, Burkard Watermann, K Gnass, A Thomsen, Susan Jobling

  Source: Environmental science & technology. 2009 Mar 15

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