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1 to 10 of 36 literature results
Chromosomal translocations are a hallmark of leukemia/lymphoma and also appear in solid tumors, but the underlying mechanism remains elusive. By estab…
Authors: Chunru Lin, Liuqing Yang, Bogdan Tanasa, Kasey Hutt, Bong-gun Ju, Kenny Ohgi, Jie Zhang, David W Rose, Xiang-Dong Fu, Christopher K Glass,…
Source: Cell. 2009 Dec 11
View Full TextWhile the transcriptional machinery has been extensively dissected at the molecular level, little is known about regulation of chromosomal organizatio…
Authors: Esperanza Nunez, Young-Soo Kwon, Kasey R Hutt, Qidong Hu, Maria Dafne Cardamone, Kenneth A Ohgi, Ivan Garcia-Bassets, David W Rose, Christopher K Glass, Michael G Rosenfeld,…
Source: Cell. 2008 Mar 21
View Full TextNuclear receptors undergo ligand-dependent conformational changes that are required for corepressor-coactivator exchange, but whether there is an actu…
Authors: Ivan Garcia-Bassets, Young-Soo Kwon, Francesca Telese, Gratien G Prefontaine, Kasey R Hutt, Christine S Cheng, Bong-Gun Ju, Kenneth A Ohgi, Jianxun Wang, Laure Escoubet-Lozach,…
Source: Cell. 2007 Feb 9
View Free Full TextA key strategy to achieve regulated gene expression in higher eukaryotes is to prevent illegitimate signal-independent activation by imposing robust c…
Authors: Valentina Perissi, Claudio Scafoglio, Jie Zhang, Kenneth A Ohgi, David W Rose, Christopher K Glass, Michael G Rosenfeld
Source: Molecular cell. 2008 Mar 28
View Free Full TextPeroxisome proliferator-activated receptor-gamma (PPAR-gamma) has essential roles in adipogenesis and glucose homeostasis, and is a molecular target o…
Authors: Gabriel Pascual, Amy L Fong, Sumito Ogawa, Amir Gamliel, Andrew C Li, Valentina Perissi, David W Rose, Timothy M Willson, Michael G Rosenfeld, Christopher K Glass
Source: Nature. 2005 Sep 29
View Free Full TextThe mechanisms that control the precisely regulated switch from gene repression to gene activation represent a central question in mammalian developme…
Authors: Valentina Perissi, Aneel Aggarwal, Christopher K Glass, David W Rose, Michael G Rosenfeld
Source: Cell. 2004 Feb 20
View Full TextDefining the precise molecular strategies that coordinate patterns of transcriptional responses to specific signals is central for understanding norma…
Authors: Ping Zhu, Sung Hee Baek, Eliot M Bourk, Kenneth A Ohgi, Ivan Garcia-Bassets, Hideki Sanjo, Shizuo Akira, Paul F Kotol, Christopher K Glass, Michael G Rosenfeld,…
Source: Cell. 2006 Feb 10
View Full TextDefining the molecular strategies that integrate diverse signalling pathways in the expression of specific gene programmes that are critical in homeos…
Authors: Jung Hwa Kim, Bogyou Kim, Ling Cai, Hee June Choi, Kenneth A Ohgi, Chris Tran, Charlie Chen, Chin Ha Chung, Otmar Huber, David W Rose,…
Source: Nature. 2005 Apr 14
View Full TextSwitching specific patterns of gene repression and activation in response to precise temporal/spatial signals is critical for normal development. Here…
Authors: Bong-Gun Ju, Derek Solum, Eun Joo Song, Kong-Joo Lee, David W Rose, Christopher K Glass, Michael G Rosenfeld
Source: Cell. 2004 Dec 17
View Full TextDefining the molecular mechanisms that integrate diverse signaling pathways at the level of gene transcription remains a central issue in biology. Her…
Authors: Sung Hee Baek, Kenneth A Ohgi, David W Rose, Edward H Koo, Christopher K Glass, Michael G Rosenfeld
Source: Cell. 2002 Jul 12
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