1 to 10 of 28 literature results

• Abnormal connexin expression underlies delayed wound healing in diabetic skin.

  OBJECTIVE: Dynamically regulated expression of the gap junction protein connexin (Cx)43 plays pivotal roles in wound healing. Cx43 is normally downreg…

  Authors: Chiuhui Mary Wang, Jill Lincoln, Jeremy E Cook, David L Becker

  Source: Diabetes. 2007 Nov

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• Acute downregulation of connexin43 at wound sites leads to a reduced inflammatory response, enhanced keratinocyte proliferation and wound fibroblast migration.

  Experimental downregulation of connexin43 (Cx43) expression at skin wound sites appears to markedly improve the rate and quality of healing, but the u…

  Authors: Ryoichi Mori, Kieran T Power, Chiuhui Mary Wang, Paul Martin, David L Becker

  Source: Journal of cell science. 2006 Dec 15

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• Myoblast proliferation and syncytial fusion both depend on connexin43 function in transfected skeletal muscle primary cultures.

  Muscles are formed by fusion of individual postmitotic myoblasts to form multinucleated syncytial myotubes. The process requires a well-coordinated tr…

  Authors: Aniko Gorbe, Tibor Krenacs, Jeremy E Cook, David L Becker

  Source: Experimental cell research. 2007 Apr 1

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• Quantification of retinal transneuronal degeneration in human glaucoma: a novel multiphoton-DAPI approach.

  PURPOSE: Glaucoma is presumed to result in the selective loss of retinal ganglion cells. In many neural systems, this loss would initiate a cascade of…

  Authors: Yuan Lei, Nigel Garrahan, Boris Hermann, David L Becker, M Rosario Hernandez, Michael E Boulton, James E Morgan

  Source: Investigative ophthalmology & visual science. 2008 May

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• Second harmonic generation confocal microscopy of collagen type I from rat tendon cryosections.

  We performed second harmonic generation (SHG) imaging of collagen in rat-tendon cryosections, using femtosecond laser scanning confocal microscopy, bo…

  Authors: Theodossis A Theodossiou, Christopher Thrasivoulou, Chidi Ekwobi, David L Becker

  Source: Biophysical journal. 2006 Dec 15

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• Mutations in the gene for connexin 26 (GJB2) that cause hearing loss have a dominant negative effect on connexin 30.

  Mutations in the gene (GJB2) encoding connexin 26 (cx26) have been linked to sensorineural hearing loss either alone or as part of a syndrome. Here we…

  Authors: Nerissa K Marziano, Stefano O Casalotti, Anne E Portelli, David L Becker, Andrew Forge

  Source: Human molecular genetics. 2003 Apr 15

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• In differentiating prefusion myoblasts connexin43 gap junction coupling is upregulated before myoblast alignment then reduced in post-mitotic cells.

  Previously we have shown that during in vivo muscle regeneration differentiating rat primary myoblasts transiently upregulate connexin43 (Cx43) gap ju…

  Authors: Aniko Gorbe, David L Becker, Laszlo Dux, Laszlo Krenacs, Tibor Krenacs

  Source: Histochemistry and cell biology. 2006 Jun

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• Follicle-stimulating hormone affects metaphase I chromosome alignment and increases aneuploidy in mouse oocytes matured in vitro.

  Follicle-Stimulating Hormone (FSH) at a wide range of doses is routinely added to culture media during in vitro maturation (IVM) of oocytes, but the e…

  Authors: Ruth Roberts, Aikaterini Iatropoulou, Daniel Ciantar, Jaroslav Stark, David L Becker, Stephen Franks, Kate Hardy

  Source: Biology of reproduction. 2005 Jan

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• Energy substrate metabolism of mouse cumulus-oocyte complexes: response to follicle-stimulating hormone is mediated by the phosphatidylinositol 3-kinase pathway and is associated with oocyte maturation.

  Successful in vitro maturation (IVM) of oocytes obtained from medium-sized antral follicles could avoid the need for superovulation for in vitro ferti…

  Authors: Ruth Roberts, Jaroslav Stark, Aikaterini Iatropoulou, David L Becker, Stephen Franks, Kate Hardy

  Source: Biology of reproduction. 2004 Jul

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• Gap junction protein expression and cellularity: comparison of immature and adult equine digital tendons.

  Injury to the energy-storing superficial digital flexor tendon is common in equine athletes and is age-related. Tenocytes in the superficial digital f…

  Authors: Rachael L Stanley, Roland A Fleck, David L Becker, Allen E Goodship, Jim R Ralphs, Janet C Patterson-Kane

  Source: Journal of anatomy. 2007 Sep

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