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Cell-based screening using phenotypic assays is a useful means of identifying bioactive chemicals for use as tools to elucidate complex cellular proce…
Authors: David C Schriemer, Danielle Kemmer, Michel Roberge
Source: Combinatorial chemistry & high throughput screening. 2008 Sep
View Full TextBACKGROUND: Single genome-wide screens for the effect of altered gene dosage on drug sensitivity in the model organism Saccharomyces cerevisiae provid…
Authors: Danielle Kemmer, Lianne M McHardy, Shawn Hoon, Delphine Rebérioux, Guri Giaever, Corey Nislow, Calvin D Roskelley, Michel Roberge
Source: BMC microbiology. 2009
View Full TextKnowledge of the spectrum of cellular proteins targeted by experimental therapeutic agents would greatly facilitate drug development. However, identif…
Authors: Christopher M Sturgeon, Danielle Kemmer, Hilary J Anderson, Michel Roberge
Source: Biotechnology journal. 2006 Mar
View Full TextBACKGROUND: We introduce the Gene Characterization Index, a bioinformatics method for scoring the extent to which a protein-encoding gene is functiona…
Authors: Danielle Kemmer, Raf M Podowski, Dimas Yusuf, Jochen Brumm, Warren Cheung, Claes Wahlestedt, Boris Lenhard, Wyeth W Wasserman
Source: PloS one. 2008
View Full TextIn this paper we aim to create a reference data collection of Northern blot results and demonstrate how such a collection can enable a quantitative co…
Authors: Danielle Kemmer, Margareta Faxén, Emily Hodges, Jonathan Lim, Elena Herzog, Elsebrit Ljungström, Anders Lundmark, Mary K Olsen, Raf Podowski, Erik L L Sonnhammer,…
Source: Comparative and functional genomics. 2004
View Free Full TextBACKGROUND: Despite significant efforts from the research community, an extensive portion of the proteins encoded by human genes lack an assigned cell…
Authors: Danielle Kemmer, Raf M Podowski, David Arenillas, Jonathan Lim, Emily Hodges, Peggy Roth, Erik L L Sonnhammer, Christer Höög, Wyeth W Wasserman
Source: BMC genomics. 2006
View Full TextWe developed Ulysses as a user-oriented system that uses a process called Interolog Analysis for the parallel analysis and display of protein interact…
Authors: Danielle Kemmer, Yong Huang, Sohrab P Shah, Jonathan Lim, Jochen Brumm, Macaire M S Yuen, John Ling, Tao Xu, Wyeth W Wasserman, B F Francis Ouellette
Source: Genome biology. 2005
View Full TextAuthors: Danielle Kemmer, Andrew Fraser
Source: Genome biology. 2002
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