1 to 2 of 2 literature results

• Cdk2 suppresses cellular senescence induced by the c-myc oncogene.

  Activated oncogenes induce compensatory tumour-suppressive responses, such as cellular senescence or apoptosis, but the signals determining the main o…

  Authors: Stefano Campaner, Mirko Doni, Per Hydbring, Alessandro Verrecchia, Lucia Bianchi, Domenico Sardella, Thomas Schleker, Daniele Perna, Susanna Tronnersjö, Matilde Murga,…

  Source: Nature cell biology. 2010 Jan

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• Tip60 is a haplo-insufficient tumour suppressor required for an oncogene-induced DNA damage response.

  The acetyl-transferase Tip60 might influence tumorigenesis in multiple ways. First, Tip60 is a co-regulator of transcription factors that either promo…

  Authors: Chiara Gorrini, Massimo Squatrito, Chiara Luise, Nelofer Syed, Daniele Perna, Landon Wark, Francesca Martinato, Domenico Sardella, Alessandro Verrecchia, Samantha Bennett,…

  Source: Nature. 2007 Aug 30

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