1 to 5 of 5 literature results

• p97: The cell's molecular purgatory?

  The multifunctional AAA-ATPase p97/VCP is one of the most extensively studied members of this protein family, yet it presents the field with many perp…

  Authors: Dalia Halawani, Martin Latterich

  Source: Molecular cell. 2006 Jun 23

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• Hereditary inclusion body myopathy-linked p97/VCP mutations in the NH2 domain and the D1 ring modulate p97/VCP ATPase activity and D2 ring conformation.

  Hereditary inclusion body myopathy associated with early-onset Paget disease of bone and frontotemporal dementia (hIBMPFTD) is a degenerative disorder…

  Authors: Dalia Halawani, Andréa C LeBlanc, Isabelle Rouiller, Stephen W Michnick, Marc J Servant, Martin Latterich

  Source: Molecular and cellular biology. 2009 Aug

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• GTPase-mediated regulation of the unfolded protein response in Caenorhabditis elegans is dependent on the AAA+ ATPase CDC-48.

  When endoplasmic reticulum (ER) homeostasis is perturbed, an adaptive mechanism is triggered and named the unfolded protein response (UPR). Thus far, …

  Authors: Marie-Elaine Caruso, Sarah Jenna, Marion Bouchecareilh, David L Baillie, Daniel Boismenu, Dalia Halawani, Martin Latterich, Eric Chevet

  Source: Molecular and cellular biology. 2008 Jul

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• p38 MAP kinase signaling is necessary for rat chondrosarcoma cell proliferation.

  Chondrosarcomas represent the second most frequent class of primary skeletal malignancies. This tumor type is highly resistant to radiation therapy an…

  Authors: Dalia Halawani, Rhoda Mondeh, Lee-Anne Stanton, Frank Beier

  Source: Oncogene. 2004 Apr 29

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• Requirements for the selective degradation of CD4 receptor molecules by the human immunodeficiency virus type 1 Vpu protein in the endoplasmic reticulum.

  BACKGROUND: HIV-1 Vpu targets newly synthesized CD4 receptor for rapid degradation by a process reminiscent of endoplasmic reticulum (ER)-associated p…

  Authors: Julie Binette, Mathieu Dubé, Johanne Mercier, Dalia Halawani, Martin Latterich, Eric A Cohen

  Source: Retrovirology. 2007

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