1 to 10 of 44 literature results

• But young researchers feel disillusioned.

  Authors: D R Dietrich, B C Hitzfeld

  Source: Nature. 2000 Apr 27

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• Oatp-associated uptake and toxicity of microcystins in primary murine whole brain cells.

  Microcystins (MCs) are naturally occurring cyclic heptapeptides that exhibit hepato-, nephro- and possibly neurotoxic effects in mammals. Organic anio…

  Authors: D Feurstein, K Holst, A Fischer, D R Dietrich

  Source: Toxicology and applied pharmacology. 2009 Jan 15

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• Physiological endpoints for potential SSRI interactions in fish.

  Selective serotonin reuptake inhibitors (SSRIs) are among the pharmaceutical compounds frequently detected in sewage treatment plant effluents and sur…

  Authors: N Kreke, D R Dietrich

  Source: Critical reviews in toxicology. 2008

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• The role of organic anion transporting polypeptides (OATPs/SLCOs) in the toxicity of different microcystin congeners in vitro: a comparison of primary human hepatocytes and OATP-transfected HEK293 cells.

  Cellular uptake of microcystins (MCs), a family of cyclic cyanobacterial heptapeptide toxins, occurs via specific organic anion transporting polypepti…

  Authors: A Fischer, S J Hoeger, K Stemmer, D J Feurstein, D Knobeloch, A Nussler, D R Dietrich

  Source: Toxicology and applied pharmacology. 2010 May 15

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• Analytical and functional characterization of microcystins [Asp3]MC-RR and [Asp3,Dhb7]MC-RR: consequences for risk assessment?

  The microcystin (MC) producing P. rubescens occurs in pre-alpine lakes and may impact fishery success, bathing, and raw water quality. P. rubescens ex…

  Authors: S J Hoeger, D Schmid, J F Blom, B Ernst, D R Dietrich

  Source: Environmental science & technology. 2007 Apr 1

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• Propiverine-induced accumulation of nuclear and cytosolic protein in F344 rat kidneys: isolation and identification of the accumulating protein.

  Male and female F344 rats but not B6C3F1 mice exposed for 104 weeks to propiverine hydrochloride (1-methylpiperid-4-yl 2,2-diphenyl-2-(1-propoxy)aceta…

  Authors: D R Dietrich, A H Heussner, E O'Brien, T Gramatté, M Runkel, S Rumpf, B W Day

  Source: Toxicology and applied pharmacology. 2008 Dec 15

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• Quantitative assessment of aerosolized cyanobacterial toxins at two New Zealand lakes.

  The cyanobacterial toxins, nodularin and microcystin, are highly efficient inhibitors of cellular protein phosphatases. Toxicity primarily evolves fol…

  Authors: S A Wood, D R Dietrich

  Source: Journal of environmental monitoring : JEM. 2011 Jun

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• Concentrations of retinol, 3,4-didehydroretinol, and retinyl esters in plasma of free-ranging birds of prey.

  This study investigated vitamin A compounds in the plasma of healthy free-ranging Central European raptors with different feeding strategies. Plasma s…

  Authors: K Müller, J Raila, R Altenkamp, D Schmidt, R Dietrich, A Hurtienne, M Wink, O Krone, L Brunnberg, F J Schweigert

  Source: Journal of animal physiology and animal nutrition. 2011 Sep 6

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• Organic anion transporting polypeptides expressed in liver and brain mediate uptake of microcystin.

  Microcystins are toxins produced by freshwater cyanobacteria. They are cyclic heptapeptides that exhibit hepato- and neurotoxicity. However, the trans…

  Authors: W J Fischer, S Altheimer, V Cattori, P J Meier, D R Dietrich, B Hagenbuch

  Source: Toxicology and applied pharmacology. 2005 Mar 15

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• The human relevant potency threshold: reducing uncertainty by human calibration of cumulative risk assessments.

  The 2008 National Research Council report "Phthalates and Cumulative Risk Assessment: Tasks Ahead," rejected the underlying premises of TEQ-like appro…

  Authors: C J Borgert, E V Sargent, G Casella, D R Dietrich, L S McCarty, R J Golden

  Source: Regulatory toxicology and pharmacology : RTP. 2012 Mar

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