1 to 10 of 396 literature results

• LXR signaling couples sterol metabolism to proliferation in the acquired immune response.

  Cholesterol is essential for membrane synthesis; however, the mechanisms that link cellular lipid metabolism to proliferation are incompletely underst…

  Authors: Steven J Bensinger, Michelle N Bradley, Sean B Joseph, Noam Zelcer, Edith M Janssen, Mary Ann Hausner, Roger Shih, John S Parks, Peter A Edwards, Beth D Jamieson,…

  Source: Cell. 2008 Jul 11

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• Synthesis of C14,15-dihydro-C22,25-epi north unit of cephalostatin 1 via "red-ox" modifications of hecogenin acetate.

  The C14,15-dihydro-C22,25-epi north unit of cephalostatin 1 has been synthesized in 11 operations from commercially available hecogenin acetate via mu…

  Authors: Seongmin Lee, Daniel Jamieson, Philip L Fuchs

  Source: Organic letters. 2009 Jan 1

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• Saving sulfur.

  Authors: Derek Jamieson

  Source: Nature genetics. 2002 Jul

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• Influence of pharmacogenetics on response and toxicity in breast cancer patients treated with doxorubicin and cyclophosphamide.

  BACKGROUND: Doxorubicin and cyclophosphamide (AC) therapy is an effective treatment for early-stage breast cancer. Doxorubicin is a substrate for ABCB…

  Authors: J Bray, J Sludden, M J Griffin, M Cole, M Verrill, D Jamieson, A V Boddy

  Source: British journal of cancer. 2010 Mar 16

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• Development and validation of cell-based ELISA for the quantification of trastuzumab in human plasma.

  Trastuzumab is a therapeutic monoclonal antibody against the Her2 oncoprotein, which is over-expressed in approximately 30% of breast cancers, and is …

  Authors: David Jamieson, Nicola Cresti, Mark W Verrill, Alan V Boddy

  Source: Journal of immunological methods. 2009 Jun 30

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• Determining the effect of highly active antiretroviral therapy on changes in human immunodeficiency virus type 1 RNA viral load using a marginal structural left-censored mean model.

  Highly active antiretroviral therapy (HAART) dramatically reduces the load of circulating human immunodeficiency virus type 1 (HIV-1) by blocking repl…

  Authors: Stephen R Cole, Miguel A Hernán, Kathryn Anastos, Beth D Jamieson, James M Robins

  Source: American journal of epidemiology. 2007 Jul 15

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• Reduction of mitomycin C is catalysed by human recombinant NRH:quinone oxidoreductase 2 using reduced nicotinamide adenine dinucleotide as an electron donating co-factor.

  NRH:Quinone Oxidoreductase 2 (NQO2) has been described as having no enzymatic activity with nicotinamide adenine dinucleotide (NADH) or NADPH as elect…

  Authors: D Jamieson, A T Y Tung, R J Knox, A V Boddy

  Source: British journal of cancer. 2006 Nov 6

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• Regulatory T cell expansion and immune activation during untreated HIV type 1 infection are associated with disease progression.

  Regulatory T cells (Tregs) may play an important role in the immunopathology of chronic HIV-1 infection due to their potent suppressive activity of bo…

  Authors: Weiwei Cao, Beth D Jamieson, Lance E Hultin, Patricia M Hultin, Roger Detels

  Source: AIDS research and human retroviruses. 2009 Feb

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• The relationship between antibody to R7V and progression of HIV type 1 infection.

  The presence of antibody to R7V (anti-R7VAb), a seven-amino acid sequence derived from beta(2)-microglobulin incorporated into HIV-1 virions from the …

  Authors: Joseph B Margolick, Jean M Da Costa Castro, Albert Sanchez, Francois Gemrot, John P Phair, Beth D Jamieson, Charles R Rinaldo, Lisa P Jacobson

  Source: AIDS research and human retroviruses. 2010 Apr

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• Bronchoalveolar immunologic profile of acute human lung transplant allograft rejection.

  Bronchoalveolar lavage fluid (BALF) offers a potential means to diagnose acute rejection and could provide insight into the immune mechanisms responsi…

  Authors: Aric L Gregson, Aki Hoji, Rajan Saggar, David J Ross, Bernard M Kubak, Beth D Jamieson, S Samuel Weigt, Joseph P Lynch, Abbas Ardehali, John A Belperio,…

  Source: Transplantation. 2008 Apr 15

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