1 to 10 of 27 literature results

• The XIST noncoding RNA functions independently of BRCA1 in X inactivation.

  Females with germline mutations in BRCA1 are predisposed to develop breast and ovarian cancers. A previous report indicated that BRCA1 colocalizes wit…

  Authors: Cuiying Xiao, Judith A Sharp, Misako Kawahara, Albert R Davalos, Michael J Difilippantonio, Ying Hu, Wenmei Li, Liu Cao, Ken Buetow, Thomas Ried,…

  Source: Cell. 2007 Mar 9

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• Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice.

  In lower eukaryotes, Sir2 serves as a histone deacetylase and is implicated in chromatin silencing, longevity, and genome stability. Here we mutated t…

  Authors: Rui-Hong Wang, Kundan Sengupta, Cuiling Li, Hyun-Seok Kim, Liu Cao, Cuiying Xiao, Sangsoo Kim, Xiaoling Xu, Yin Zheng, Beverly Chilton,…

  Source: Cancer cell. 2008 Oct 7

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• Interplay among BRCA1, SIRT1, and Survivin during BRCA1-associated tumorigenesis.

  Germline mutations of BRCA1 predispose women to breast and ovarian cancers. However, the downstream mediators of BRCA1 function in tumor suppression r…

  Authors: Rui-Hong Wang, Yin Zheng, Hyun-Seok Kim, Xiaoling Xu, Liu Cao, Tyler Luhasen, Mi-Hye Lee, Cuiying Xiao, Athanassios Vassilopoulos, Weiping Chen,…

  Source: Molecular cell. 2008 Oct 10

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• Absence of the full-length breast cancer-associated gene-1 leads to increased expression of insulin-like growth factor signaling axis members.

  The breast cancer-associated gene-1 (BRCA1) plays many important functions in multiple biological processes/pathways. Mice homozygous for a targeted d…

  Authors: Vivek Shukla, Xavier Coumoul, Liu Cao, Rui-Hong Wang, Cuiying Xiao, Xiaoling Xu, Sebastiano Andò, Shoshana Yakar, Derek Leroith, Chuxia Deng

  Source: Cancer research. 2006 Jul 15

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• Preliminary study of the relationship between DAZ gene copy deletions and spermatogenic impairment in Chinese men.

  Copy deletion screening of DAZ gene family on the Y chromosome in 485 patients with idiopathic azoospermia or oligozoospermia and 236 fertile men reve…

  Authors: Yuan Yang, Cuiying Xiao, Sizhong Zhang, A Zhoucun, Xiang Li, Sixiao Zhang

  Source: Fertility and sterility. 2006 Apr

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• Clustering of variations and haplotype analysis in the highly variable region of exon 11 of BRCA1 in Chinese women with sporadic breast cancer.

  Studies on mutations of BRCA1 gene in Oriental populations, especially in Chinese are sparse. To evaluate the contribution of BRCA1 mutations to spora…

  Authors: Yunqing Li, Sizhong Zhang, Cuiying Xiao, Zhiguang Su, YangBing Zhao, Wei Chen, Ge Zhang

  Source: Human mutation. 2002 Nov

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• PKHD1 gene silencing may cause cell abnormal proliferation through modulation of intracellular calcium in autosomal recessive polycystic kidney disease.

  Autosomal recessive polycystic kidney disease (ARPKD) is one of the important genetic disorders in pediatric practice. Mutation of the polycystic kidn…

  Authors: Jiyun Yang, Sizhong Zhang, Qin Zhou, Hong Guo, Ke Zhang, Rong Zheng, Cuiying Xiao

  Source: Journal of biochemistry and molecular biology. 2007 Jul 31

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• Molecular cloning and characterization of a mouse spermatogenesis-related ring finger gene znf230.

  Complete cDNA of mouse gene znf230 was cloned by rapid amplification of cDNA ends (RACE). This cDNA is 982 base pairs (bp) in length and encodes a 230…

  Authors: Weimin Qiu, Sizhong Zhang, Cuiying Xiao, Wenmin Xu, Yongxin Ma, Yunqiang Liu, Qiaqing Wu

  Source: Biochemical and biophysical research communications. 2003 Jun 27

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• A novel allele in the promoter of the hepatic lipase is associated with increased concentration of HDL-C and decreased promoter activity.

  Hepatic lipase (HL) is a lipolytic enzyme involved in the metabolism of plasma lipoproteins, especially HDLs. Association of the polymorphisms in the …

  Authors: Zhiguang Su, Sizhong Zhang, Daniel W Nebert, Li Zhang, Dejia Huang, Yiping Hou, Linchuan Liao, Cuiying Xiao

  Source: Journal of lipid research. 2002 Oct

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• 8302A/C and (TTA)n polymorphisms in the HMG-CoA reductase gene may be associated with some plasma lipid metabolic phenotypes in patients with coronary heart disease.

  HMG-CoA reductase (HMGCR) is a rate-limiting enzyme that participates in cholesterol metabolism. Here we analyzed the 8302A/C and the (TTA)n polymorph…

  Authors: Yu Tong, Sizhong Zhang, Hai Li, Zhiguang Su, Xiangdong Kong, Hekun Liu, Cuiying Xiao, Yan Sun, Jia Jun Shi

  Source: Lipids. 2004 Mar

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