1 to 10 of 135 literature results

• Inhibition of carcinogenesis by tea.

  Tea has received a great deal of attention because tea polyphenols are strong antioxidants, and tea preparations have inhibitory activity against tumo…

  Authors: Chung S Yang, Pius Maliakal, Xiaofeng Meng

  Source: Annual review of pharmacology and toxicology. 2002

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• Inhibition of adenoma progression to adenocarcinoma in a 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis model in A/J mice by tea polyphenols and caffeine.

  The present study investigated the inhibitory effects of Polyphenon E [a standardized green tea polyphenol preparation containing 65% (-)-epigallocate…

  Authors: Gang Lu, Jie Liao, Guangyu Yang, Kenneth R Reuhl, Xingpei Hao, Chung S Yang

  Source: Cancer research. 2006 Dec 1

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• Cancer Preventive Activities of Tocopherols and Tocotrienols.

  The cancer preventive activity of vitamin E has been studied. Whereas some epidemiological studies have suggested a protective effect of vitamin E aga…

  Authors: Jihyeung Ju, Sonia C Picinich, Zhihong Yang, Yang Zhao, Nanjoo Suh, Ah-Ng Kong, Chung S Yang

  Source: Carcinogenesis. 2009 Sep 11

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• Inhibition of carcinogenesis by tea constituents.

  The possible cancer preventive activity of tea has received much attention in recent years. The inhibitory activities of tea and tea constituents agai…

  Authors: Jihyeung Ju, Gang Lu, Joshua D Lambert, Chung S Yang

  Source: Seminars in cancer biology. 2007 Oct

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• Green tea polyphenols inhibit colorectal aberrant crypt foci (ACF) formation and prevent oncogenic changes in dysplastic ACF in azoxymethane-treated F344 rats.

  Green tea and its constituents have shown cancer-preventive activities in many animal models. In order to prepare for a human trial on the inhibition …

  Authors: Hang Xiao, Xingpei Hao, Barbara Simi, Jihyeung Ju, Heyuan Jiang, Bandaru S Reddy, Chung S Yang

  Source: Carcinogenesis. 2008 Jan

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• Metabolism of dietary polyphenols and possible interactions with drugs.

  Polyphenolic compounds are abundant in the human diet and gram quantities are ingested daily. The consumption of polyphenols is expected to rise due t…

  Authors: Joshua D Lambert, Shengmin Sang, Anthony Y H Lu, Chung S Yang

  Source: Current drug metabolism. 2007 Jun

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• Mechanism of action of (-)-epigallocatechin-3-gallate: auto-oxidation-dependent inactivation of epidermal growth factor receptor and direct effects on growth inhibition in human esophageal cancer KYSE 150 cells.

  Epigallocatechin-3-gallate (EGCG), the principal polyphenol in green tea, has been shown to inhibit the growth of many cancer cell lines and to suppre…

  Authors: Zhe Hou, Shengmin Sang, Hui You, Mao-Jung Lee, Jungil Hong, Khew-Voon Chin, Chung S Yang

  Source: Cancer research. 2005 Sep 1

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• Involvement of the 5-lipoxygenase/leukotriene A4 hydrolase pathway in 7,12-dimethylbenz[a]anthracene (DMBA)-induced oral carcinogenesis in hamster cheek pouch, and inhibition of carcinogenesis by its inhibitors.

  Previous studies have shown that aberrant arachidonic acid (AA) metabolism, especially cyclooxygenase-2 (Cox-2) and 5-lipoxygenase (5-Lox) pathways, a…

  Authors: Zheng Sun, Sandeep Sood, Ning Li, Divya Ramji, Peiying Yang, Robert A Newman, Chung S Yang, Xiaoxin Chen

  Source: Carcinogenesis. 2006 Sep

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• Inhibition of intestinal tumorigenesis in Apcmin/+ mice by (-)-epigallocatechin-3-gallate, the major catechin in green tea.

  The present study was designed to investigate the effects of two main constituents of green tea, (-)-epigallocatechin-3-gallate (EGCG) and caffeine, o…

  Authors: Jihyeung Ju, Jungil Hong, Jian-nian Zhou, Zui Pan, Mousumi Bose, Jie Liao, Guang-yu Yang, Ying Ying Liu, Zhe Hou, Yong Lin,…

  Source: Cancer research. 2005 Nov 15

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• Effect of genistein on the bioavailability and intestinal cancer chemopreventive activity of (-)-epigallocatechin-3-gallate.

  The green tea (Camellia sinensis) catechin, (-)-epigallocatechin-3-gallate (EGCG), has shown cancer-preventive activity in animal models. Previously, …

  Authors: Joshua D Lambert, Seok-Joo Kwon, Jihyeung Ju, Mousumi Bose, Mao-Jung Lee, Jungil Hong, Xingpei Hao, Chung S Yang

  Source: Carcinogenesis. 2008 Oct

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