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10 literature results
An appropriate beta cell mass is pivotal for the maintenance of glucose homeostasis. Both insulin and IGF-1 are important in regulation of beta cell g…
Authors: Kohjiro Ueki, Terumasa Okada, Jiang Hu, Chong Wee Liew, Anke Assmann, Gabriella M Dahlgren, Jennifer L Peters, Jonathan G Shackman, Min Zhang, Isabella Artner,…
Source: Nature genetics. 2006 May
View Full TextMelanin concentrating hormone (MCH) is a hypothalamic neuropeptide known to play a critical role in energy balance. We have previously reported that o…
Authors: Pavlos Pissios, Umut Ozcan, Efi Kokkotou, Terumasa Okada, Chong Wee Liew, Siming Liu, Jennifer N Peters, Gabriella Dahlgren, Jason Karamchandani, Yogish C Kudva,…
Source: Diabetes. 2007 Feb
View Full TextLKB1 is a tumor suppressor that may also be fundamental to cell metabolism, since LKB1 phosphorylates and activates the energy sensing enzyme AMPK. We…
Authors: Ho-Jin Koh, David E Arnolds, Nobuharu Fujii, Thien T Tran, Marc J Rogers, Niels Jessen, Yangfeng Li, Chong Wee Liew, Richard C Ho, Michael F Hirshman,…
Source: Molecular and cellular biology. 2006 Nov
View Free Full TextThe presence of heterotrimeric G-proteins at epithelial tight junctions suggests that these cellular junctions are regulated by so far unknown G-prote…
Authors: Chong Wee Liew, Matthias Vockel, Günter Glassmeier, Johanna M Brandner, Gregorio J Fernandez-Ballester, Jürgen R Schwarz, Stefan Schulz, Friedrich Buck, Luis Serrano, Dietmar Richter,…
Source: FEBS letters. 2009 Jan 5
View Full TextPatients with type 2 diabetes lose beta cells, but the underlying mechanisms are incompletely understood. Glucose-6-phosphate dehydrogenase (G6PD) is …
Authors: Zhaoyun Zhang, Chong Wee Liew, Diane E Handy, Yingyi Zhang, Jane A Leopold, Ji Hu, Lili Guo, Rohit N Kulkarni, Joseph Loscalzo, Robert C Stanton
Source: The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2009 Dec 23
View Full TextInsulin/IGF-I signaling regulates the metabolism of most mammalian tissues including pancreatic islets. To dissect the mechanisms linking insulin sign…
Authors: Siming Liu, Terumasa Okada, Anke Assmann, Jamie Soto, Chong Wee Liew, Heiko Bugger, Orian S Shirihai, E Dale Abel, Rohit N Kulkarni
Source: PloS one. 2009
View Full TextGlucagon plays an important role in glucose homeostasis by regulating hepatic glucose output in both normo- and hypoglycemic conditions. In this study…
Authors: Dan Kawamori, Amarnath J Kurpad, Jiang Hu, Chong Wee Liew, Judy L Shih, Eric L Ford, Pedro L Herrera, Kenneth S Polonsky, Owen P McGuinness, Rohit N Kulkarni
Source: Cell metabolism. 2009 Apr
View Full TextLeucine-rich repeat and PDZ [postsynaptic density-95 (PSD-95)/Discs large/zona occludens-1] domain proteins such as scribble and Densin-180 have been …
Authors: Arne Quitsch, Kerstin Berhörster, Chong Wee Liew, Dietmar Richter, Hans-Jürgen Kreienkamp
Source: The Journal of neuroscience : the official journal of the Society for Neuroscience. 2005 Jan 12
View Full TextInsulin and insulin-like growth factor 1 (IGF1) are ubiquitous growth factors that regulate proliferation in most mammalian tissues including pancreat…
Authors: Terumasa Okada, Chong Wee Liew, Jiang Hu, Charlotte Hinault, M Dodson Michael, Jan Krtzfeldt, Catherine Yin, Martin Holzenberger, Markus Stoffel, Rohit N Kulkarni
Source: Proceedings of the National Academy of Sciences of the United States of America. 2007 May 22
View Free Full TextDuring fasting, increased concentrations of circulating catecholamines promote the mobilization of lipid stores from adipose tissue in part by phospho…
Authors: Ling Qi, Jose E Heredia, Judith Y Altarejos, Robert Screaton, Naomi Goebel, Sherry Niessen, Ian X Macleod, Chong Wee Liew, Rohit N Kulkarni, James Bain,…
Source: Science (New York, N.Y.). 2006 Jun 23
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