1 to 4 of 4 literature results

• Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication.

  Early tumorigenesis is associated with the engagement of the DNA-damage checkpoint response (DDR). Cell proliferation and transformation induced by on…

  Authors: Raffaella Di Micco, Marzia Fumagalli, Angelo Cicalese, Sara Piccinin, Patrizia Gasparini, Chiara Luise, Catherine Schurra, Massimiliano Garre', Paolo Giovanni Nuciforo, Aaron Bensimon,…

  Source: Nature. 2006 Nov 30

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• Tip60 is a haplo-insufficient tumour suppressor required for an oncogene-induced DNA damage response.

  The acetyl-transferase Tip60 might influence tumorigenesis in multiple ways. First, Tip60 is a co-regulator of transcription factors that either promo…

  Authors: Chiara Gorrini, Massimo Squatrito, Chiara Luise, Nelofer Syed, Daniele Perna, Landon Wark, Francesca Martinato, Domenico Sardella, Alessandro Verrecchia, Samantha Bennett,…

  Source: Nature. 2007 Aug 30

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• Complex engagement of DNA damage response pathways in human cancer and in lung tumor progression.

  Tumor initiation and progression provide a multitude of occasions for the generation of DNA damage and the consequent activation of the DNA damage res…

  Authors: Paolo Giovanni Nuciforo, Chiara Luise, Maria Capra, Giuseppe Pelosi, Fabrizio d'Adda di Fagagna

  Source: Carcinogenesis. 2007 Oct

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• Pirin delocalization in melanoma progression identified by high content immuno-detection based approaches.

  BACKGROUND: Pirin (PIR) is a highly conserved nuclear protein originally isolated as an interactor of NFI/CTF1 transcription/replication factor. It is…

  Authors: Silvia Licciulli, Chiara Luise, Andrea Zanardi, Luca Giorgetti, Giuseppe Viale, Luisa Lanfrancone, Roberta Carbone, Myriam Alcalay

  Source: BMC cell biology. 2010

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