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Chemopreventive effects of natural dietary compounds on cancer development.
Chemoprevention, a relatively new and promising strategy to prevent cancer, is defined as the use of natural dietary compounds and/or synthetic substa…
Authors: Min-Hsiung Pan, Chi-Tang Ho
Source: Chemical Society reviews. 2008 Nov
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Polyphenolic chemistry of tea and coffee: a century of progress.
Tea and coffee, the most popular beverages in the world, have been consumed for thousands of years for their alluring flavors and health benefits. Pol…
Authors: Yu Wang, Chi-Tang Ho
Source: Journal of agricultural and food chemistry. 2009 Sep 23
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Chemoprevention of familial adenomatous polyposis by natural dietary compounds sulforaphane and dibenzoylmethane alone and in combination in ApcMin/+ mouse.
Cancer chemopreventive agent sulforaphane (SFN) and dibenzoylmethane (DBM) showed antitumorigenesis effects in several rodent carcinogenesis models. I…
Authors: Guoxiang Shen, Tin Oo Khor, Rong Hu, Siwang Yu, Sujit Nair, Chi-Tang Ho, Bandaru S Reddy, Mou-Tuan Huang, Harold L Newmark, Ah-Ng Tony Kong
Source: Cancer research. 2007 Oct 15
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Pterostilbene inhibited tumor invasion via suppressing multiple signal transduction pathways in human hepatocellular carcinoma cells.
Pterostilbene, a natural dimethylated analog of resveratrol, is known to have diverse pharmacologic activities including anticancer, anti-inflammation…
Authors: Min-Hsiung Pan, Yi-Siou Chiou, Wei-Jen Chen, Ju-Ming Wang, Vladimir Badmaev, Chi-Tang Ho
Source: Carcinogenesis. 2009 Jul
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Comparison of 2-acetylfuran formation between ribose and glucose in the Maillard reaction.
Sugar type is a major factor regulating the reaction rates and pathways in Maillard reaction. Ribose and glucose were used to compare their reactiviti…
Authors: Yu Wang, Chi-Tang Ho
Source: Journal of agricultural and food chemistry. 2008 Dec 24
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Formation of 2,5-dimethyl-4-hydroxy-3(2H)-furanone through methylglyoxal: a Maillard reaction intermediate.
The caramel-like aroma compound, 2,5-dimethyl-4-hydroxy-3(2H)-furanone (DMHF) was quantified and verified by HPLC and GC-MS in the Maillard reaction b…
Authors: Yu Wang, Chi-Tang Ho
Source: Journal of agricultural and food chemistry. 2008 Aug 27
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Theanaphthoquinone inhibits fatty acid synthase expression in EGF-stimulated human breast cancer cells via the regulation of EGFR/ErbB-2 signaling.
Fatty acid synthase (FAS) is a major lipogenic enzyme catalyzing the synthesis of long-chain saturated fatty acids. Most breast cancers require lipoge…
Authors: Meng-Shih Weng, Chi-Tang Ho, Yuan-Soon Ho, Jen-Kun Lin
Source: Toxicology and applied pharmacology. 2007 Jan 15
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Biotransformation of sesaminol triglucoside to mammalian lignans by intestinal microbiota.
Plant lignans occur widely in foods, with flaxseed recognized as their richest source. Some plant lignans can be converted by intestinal microbiota to…
Authors: Kuo-Ching Jan, Lucy Sun Hwang, Chi-Tang Ho
Source: Journal of agricultural and food chemistry. 2009 Jul 22
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Modulation of inflammatory genes by natural dietary bioactive compounds.
Several epidemiologic studies have shown that chronic inflammation predisposes individuals to various types of cancer. Many cancers arise from sites o…
Authors: Min-Hsiung Pan, Ching-Shu Lai, Slavik Dushenkov, Chi-Tang Ho
Source: Journal of agricultural and food chemistry. 2009 Jun 10
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Anti-inflammatory and antitumor promotional effects of a novel urinary metabolite, 3',4'-didemethylnobiletin, derived from nobiletin.
We reported previously that 3',4'-didemethylnobiletin (DDMN) is the major metabolite of nobiletin in mouse urine. In this study, we examined DDMN's mo…
Authors: Ching-Shu Lai, Shiming Li, Chee-Yin Chai, Chih-Yu Lo, Slavik Dushenkov, Chi-Tang Ho, Min-Hsiung Pan, Ying-Jan Wang
Source: Carcinogenesis. 2008 Dec
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