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• Requirement for NF-kappaB signalling in a mouse model of lung adenocarcinoma.

  NF-kappaB transcription factors function as crucial regulators of inflammatory and immune responses as well as of cell survival. They have also been i…

  Authors: Etienne Meylan, Alison L Dooley, David M Feldser, Lynn Shen, Erin Turk, Chensi Ouyang, Tyler Jacks

  Source: Nature. 2009 Nov 5

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• Sprouty-2 regulates oncogenic K-ras in lung development and tumorigenesis.

  Somatic activation of Ras occurs frequently in human cancers, including one-third of lung cancers. Activating Ras mutations also occur in the germline…

  Authors: Alice T Shaw, Alexander Meissner, James A Dowdle, Denise Crowley, Margaret Magendantz, Chensi Ouyang, Tiziana Parisi, Jayaraj Rajagopal, Leah J Blank, Roderick T Bronson,…

  Source: Genes & development. 2007 Mar 15

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