1 to 10 of 47 literature results

• CDK inhibitor p18(INK4c) is a downstream target of GATA3 and restrains mammary luminal progenitor cell proliferation and tumorigenesis.

  Mammary epithelia are composed of luminal and myoepithelial/basal cells whose neoplastic transformations lead to distinct types of breast cancers with…

  Authors: Xin-Hai Pei, Feng Bai, Matthew D Smith, Jerry Usary, Cheng Fan, Sung-Yun Pai, I-Cheng Ho, Charles M Perou, Yue Xiong

  Source: Cancer cell. 2009 May 5

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• A novel lung metastasis signature links Wnt signaling with cancer cell self-renewal and epithelial-mesenchymal transition in basal-like breast cancer.

  The establishment of metastasis depends on the ability of cancer cells to acquire a migratory phenotype combined with their capacity to recreate a sec…

  Authors: Theresa A DiMeo, Kristen Anderson, Pushkar Phadke, Cheng Fan, Chang Feng, Charles M Perou, Steven Naber, Charlotte Kuperwasser

  Source: Cancer research. 2009 Jul 1

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• LKB1 modulates lung cancer differentiation and metastasis.

  Germline mutation in serine/threonine kinase 11 (STK11, also called LKB1) results in Peutz-Jeghers syndrome, characterized by intestinal hamartomas an…

  Authors: Hongbin Ji, Matthew R Ramsey, D Neil Hayes, Cheng Fan, Kate McNamara, Piotr Kozlowski, Chad Torrice, Michael C Wu, Takeshi Shimamura, Samanthi A Perera,…

  Source: Nature. 2007 Aug 16

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• 2-methoxyestradiol inhibits the anaphase-promoting complex and protein translation in human breast cancer cells.

  2-methoxyestradiol (2ME2), an estradiol metabolite with antiproliferative and antiangiogenic activities, is in phase I/II clinical trials for breast c…

  Authors: Rajendra Bhati, Yesim Gökmen-Polar, George W Sledge, Cheng Fan, Harikrishna Nakshatri, David Ketelsen, Christoph H Borchers, Michael J Dial, Cam Patterson, Nancy Klauber-DeMore

  Source: Cancer research. 2007 Jan 15

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• Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics.

  Metaplastic breast cancers (MBC) are aggressive, chemoresistant tumors characterized by lineage plasticity. To advance understanding of their pathogen…

  Authors: Bryan T Hennessy, Ana-Maria Gonzalez-Angulo, Katherine Stemke-Hale, Michael Z Gilcrease, Savitri Krishnamurthy, Ju-Seog Lee, Jane Fridlyand, Aysegul Sahin, Roshan Agarwal, Corwin Joy,…

  Source: Cancer research. 2009 May 15

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• Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry for genotyping of human platelet-specific antigens.

  BACKGROUND: Genotyping of single-nucleotide polymorphisms (SNPs) using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (M…

  Authors: Henk S P Garritsen, Alex Xiu-Cheng Fan, Nicole Bosse, Horst Hannig, Reinhard Kelsch, Hartmut Kroll, Wolfgang Holzgreve, Xiao Yan Zhong

  Source: Transfusion. 2009 Feb

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• HPLC-DAD and HPLC-ESI-MS separation, determination and identification of the spin-labeled diastereoisomers of podophyllotoxin.

  Spin-labeled nitroxide derivatives of podophyllotoxin had better antitumor activity and less toxicity than that of the parent compounds. However, the …

  Authors: Lei Zhao, Zhen-Ling Liu, Peng-Cheng Fan, Zhi-Wei Zhang, Xiong Liu, Yun-Jing Zhan, Xuan Tian

  Source: Journal of separation science. 2009 May

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• Mitochondrial DNA content in paired normal and cancerous breast tissue samples from patients with breast cancer.

  INTRODUCTION: We develop a multiplex quantitative real-time PCR for synchronized analysis of mitochondrial DNA (mtDNA) and nuclear DNA (nDNA) to inves…

  Authors: Alex Xiu-Cheng Fan, Ramin Radpour, Mahdi Montazer Haghighi, Corina Kohler, Peng Xia, Sinuhe Hahn, Wolfgang Holzgreve, Xiao Yan Zhong

  Source: Journal of cancer research and clinical oncology. 2009 Aug

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• Comparison of serum VEGF and its soluble receptor sVEGFR1 with serum cell-free DNA in patients with breast tumor.

  BACKGROUND: The observed elevated levels of vascular endothelial growth factor (VEGF), its soluble receptor (sVEGFR1) and cell-free DNA (cfDNA) in the…

  Authors: Shereen El Tarhouny, Martin Seefeld, Alex Xiu-Cheng Fan, Sinuhe Hahn, Wolfgang Holzgreve, Xiao Yan Zhong

  Source: Cytokine. 2008 Oct

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• PGE2 and LTB4 tissue levels in benign and cancerous prostates.

  PGE2 and LTB4 are involved in inflammation and carcinogenesis in several tissues but have not been studied in prostate cancer and hyperplasia until no…

  Authors: Stéphane Larré, Nguyen Tran, Cheng Fan, Hikmat Hamadeh, Jaqueline Champigneulles, Rahmène Azzouzi, Olivier Cussenot, Philippe Mangin, Jean Luc Olivier

  Source: Prostaglandins & other lipid mediators. 2008 Dec

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