1 to 4 of 4 literature results

• The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells.

  Oct4 and Nanog are transcription factors required to maintain the pluripotency and self-renewal of embryonic stem (ES) cells. Using the chromatin immu…

  Authors: Yuin-Han Loh, Qiang Wu, Joon-Lin Chew, Vinsensius B Vega, Weiwei Zhang, Xi Chen, Guillaume Bourque, Joshy George, Bernard Leong, Jun Liu,…

  Source: Nature genetics. 2006 Apr

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• Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project.

  We report the generation and analysis of functional data from multiple, diverse experiments performed on a targeted 1% of the human genome as part of …

  Authors: ENCODE Project Consortium, Ewan Birney, John A Stamatoyannopoulos, Anindya Dutta, Roderic Guigó, Thomas R Gingeras, Elliott H Margulies, Zhiping Weng, Michael Snyder, Emmanouil T Dermitzakis,…

  Source: Nature. 2007 Jun 14

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• Deregulated direct targets of the hepatitis B virus (HBV) protein, HBx, identified through chromatin immunoprecipitation and expression microarray profiling.

  The hepatitis B-X (HBx) protein is strongly associated with hepatocellular carcinoma. It is implicated not to directly cause cancer but to play a role…

  Authors: Wing-Kin Sung, Yiwei Lu, Charlie W H Lee, Dongwei Zhang, Mostafa Ronaghi, Caroline G L Lee

  Source: The Journal of biological chemistry. 2009 Aug 14

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• Global mapping of c-Myc binding sites and target gene networks in human B cells.

  The protooncogene MYC encodes the c-Myc transcription factor that regulates cell growth, cell proliferation, cell cycle, and apoptosis. Although dereg…

  Authors: Karen I Zeller, XiaoDong Zhao, Charlie W H Lee, Kuo Ping Chiu, Fei Yao, Jason T Yustein, Hong Sain Ooi, Yuriy L Orlov, Atif Shahab, How Choong Yong,…

  Source: Proceedings of the National Academy of Sciences of the United States of America. 2006 Nov 21

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