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The hepatitis C virus (HCV) is a remarkably successful pathogen, establishing persistent infection in more than two-thirds of those who contract it. I…
Authors: Lynn B Dustin, Charles M Rice
Source: Annual review of immunology. 2007
View Full TextHepatitis C virus (HCV) is a leading cause of liver disease worldwide. The development of much needed specific antiviral therapies and an effective va…
Authors: Alexander Ploss, Matthew J Evans, Valeriya A Gaysinskaya, Maryline Panis, Hana You, Ype P de Jong, Charles M Rice
Source: Nature. 2009 Feb 12
View Free Full TextHepatitis C virus is a major global health problem affecting an estimated 170 million people worldwide. Chronic infection is common and can lead to ci…
Authors: Ivo C Lorenz, Joseph Marcotrigiano, Thomas G Dentzer, Charles M Rice
Source: Nature. 2006 Aug 17
View Full TextSince the discovery of the hepatitis C virus over 15 years ago, scientists have raced to develop diagnostics, study the virus and find new therapies. …
Authors: Brett D Lindenbach, Charles M Rice
Source: Nature. 2005 Aug 18
View Full TextHepatitis C virus (HCV) is a human pathogen affecting nearly 3% of the world's population. Chronic infections can lead to cirrhosis and liver cancer. …
Authors: Timothy L Tellinghuisen, Joseph Marcotrigiano, Charles M Rice
Source: Nature. 2005 May 19
View Free Full TextHepatitis C virus (HCV) causes chronic liver disease and affects an estimated 3% of the world's population. Options for the prevention or therapy of H…
Authors: Alexander Ploss, Charles M Rice
Source: EMBO reports. 2009 Nov
View Full TextHepatitis C virus (HCV) is a leading cause of cirrhosis and liver cancer worldwide. A better understanding of the viral life cycle, including the mech…
Authors: Matthew J Evans, Thomas von Hahn, Donna M Tscherne, Andrew J Syder, Maryline Panis, Benno Wölk, Theodora Hatziioannou, Jane A McKeating, Paul D Bieniasz, Charles M Rice
Source: Nature. 2007 Apr 12
View Full TextThe hepatitis C virus (HCV) genomic RNA possesses conserved structural elements that are essential for its replication. The 3' nontranslated region (N…
Authors: Shihyun You, Charles M Rice
Source: Journal of virology. 2008 Jan
View Free Full TextAuthors: Charles M Rice
Source: Nature. 2003 Nov 13
View Full TextBACKGROUND & AIMS: Broadly reactive neutralizing antibodies (nAbs) and multispecific T-cell responses are generated during chronic hepatitis C virus (…
Authors: Thomas von Hahn, Joo Chun Yoon, Harvey Alter, Charles M Rice, Barbara Rehermann, Peter Balfe, Jane A McKeating
Source: Gastroenterology. 2007 Feb
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