1 to 10 of 106 literature results

• Flying under the radar: the immunobiology of hepatitis C.

  The hepatitis C virus (HCV) is a remarkably successful pathogen, establishing persistent infection in more than two-thirds of those who contract it. I…

  Authors: Lynn B Dustin, Charles M Rice

  Source: Annual review of immunology. 2007

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• Human occludin is a hepatitis C virus entry factor required for infection of mouse cells.

  Hepatitis C virus (HCV) is a leading cause of liver disease worldwide. The development of much needed specific antiviral therapies and an effective va…

  Authors: Alexander Ploss, Matthew J Evans, Valeriya A Gaysinskaya, Maryline Panis, Hana You, Ype P de Jong, Charles M Rice

  Source: Nature. 2009 Feb 12

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• Structure of the catalytic domain of the hepatitis C virus NS2-3 protease.

  Hepatitis C virus is a major global health problem affecting an estimated 170 million people worldwide. Chronic infection is common and can lead to ci…

  Authors: Ivo C Lorenz, Joseph Marcotrigiano, Thomas G Dentzer, Charles M Rice

  Source: Nature. 2006 Aug 17

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• Unravelling hepatitis C virus replication from genome to function.

  Since the discovery of the hepatitis C virus over 15 years ago, scientists have raced to develop diagnostics, study the virus and find new therapies. …

  Authors: Brett D Lindenbach, Charles M Rice

  Source: Nature. 2005 Aug 18

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• Structure of the zinc-binding domain of an essential component of the hepatitis C virus replicase.

  Hepatitis C virus (HCV) is a human pathogen affecting nearly 3% of the world's population. Chronic infections can lead to cirrhosis and liver cancer. …

  Authors: Timothy L Tellinghuisen, Joseph Marcotrigiano, Charles M Rice

  Source: Nature. 2005 May 19

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• Towards a small animal model for hepatitis C.

  Hepatitis C virus (HCV) causes chronic liver disease and affects an estimated 3% of the world's population. Options for the prevention or therapy of H…

  Authors: Alexander Ploss, Charles M Rice

  Source: EMBO reports. 2009 Nov

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• Claudin-1 is a hepatitis C virus co-receptor required for a late step in entry.

  Hepatitis C virus (HCV) is a leading cause of cirrhosis and liver cancer worldwide. A better understanding of the viral life cycle, including the mech…

  Authors: Matthew J Evans, Thomas von Hahn, Donna M Tscherne, Andrew J Syder, Maryline Panis, Benno Wölk, Theodora Hatziioannou, Jane A McKeating, Paul D Bieniasz, Charles M Rice

  Source: Nature. 2007 Apr 12

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• 3' RNA elements in hepatitis C virus replication: kissing partners and long poly(U).

  The hepatitis C virus (HCV) genomic RNA possesses conserved structural elements that are essential for its replication. The 3' nontranslated region (N…

  Authors: Shihyun You, Charles M Rice

  Source: Journal of virology. 2008 Jan

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• Virology: fresh assault on hepatitis C.

  Authors: Charles M Rice

  Source: Nature. 2003 Nov 13

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• Hepatitis C virus continuously escapes from neutralizing antibody and T-cell responses during chronic infection in vivo.

  BACKGROUND & AIMS: Broadly reactive neutralizing antibodies (nAbs) and multispecific T-cell responses are generated during chronic hepatitis C virus (…

  Authors: Thomas von Hahn, Joo Chun Yoon, Harvey Alter, Charles M Rice, Barbara Rehermann, Peter Balfe, Jane A McKeating

  Source: Gastroenterology. 2007 Feb

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