1 to 6 of 6 literature results

• Distinct stem cell myeloproliferative/T lymphoma syndromes induced by ZNF198-FGFR1 and BCR-FGFR1 fusion genes from 8p11 translocations.

  8p11 myeloproliferative syndrome (EMS) is a hematopoietic stem cell disorder characterized by myeloid hyperplasia and non-Hodgkin's lymphoma with chro…

  Authors: Sergei Roumiantsev, Daniela S Krause, Carola A Neumann, Christopher A Dimitri, Frances Asiedu, Nicholas C P Cross, Richard A Van Etten

  Source: Cancer cell. 2004 Mar

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• Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumour suppression.

  Reactive oxygen species are involved in many cellular metabolic and signalling processes and are thought to have a role in disease, particularly in ca…

  Authors: Carola A Neumann, Daniela S Krause, Christopher V Carman, Shampa Das, Devendra P Dubey, Jennifer L Abraham, Roderick T Bronson, Yuko Fujiwara, Stuart H Orkin, Richard A Van Etten

  Source: Nature. 2003 Jul 31

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• Genetic replacement of cyclin D1 function in mouse development by cyclin D2.

  D cyclins (D1, D2, and D3) are components of the core cell cycle machinery in mammalian cells. It is unclear whether each of the D cyclins performs un…

  Authors: Bradley C Carthon, Carola A Neumann, Manjusri Das, Basil Pawlyk, Tiansen Li, Yan Geng, Piotr Sicinski

  Source: Molecular and cellular biology. 2005 Feb

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• Peroxiredoxin 1 and its role in cell signaling.

  Peroxiredoxins (Prdxs) are a family of small (22-27 kDa) nonseleno peroxidases currently known to possess six mammalian isoforms. Although their indiv…

  Authors: Carola A Neumann, Juxiang Cao, Yefim Manevich

  Source: Cell cycle (Georgetown, Tex.). 2009 Dec 15

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• Autophagy regulates keratin 8 homeostasis in mammary epithelial cells and in breast tumors.

  Autophagy is activated in response to cellular stressors and mediates lysosomal degradation and recycling of cytoplasmic material and organelles as a …

  Authors: Sameera Kongara, Olga Kravchuk, Irina Teplova, Fred Lozy, Jennifer Schulte, Dirk Moore, Nicola Barnard, Carola A Neumann, Eileen White, Vassiliki Karantza

  Source: Molecular cancer research : MCR. 2010 Jun

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• Prdx1 inhibits tumorigenesis via regulating PTEN/AKT activity.

  It is widely accepted that reactive oxygen species (ROS) promote tumorigenesis. However, the exact mechanisms are still unclear. As mice lacking the p…

  Authors: Juxiang Cao, Jennifer Schulte, Alexander Knight, Nicholas R Leslie, Agnieszka Zagozdzon, Roderick Bronson, Yefim Manevich, Craig Beeson, Carola A Neumann

  Source: The EMBO journal. 2009 May 20

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