1 to 10 of 88 literature results

• Myosin II and mechanotransduction: a balancing act.

  Adherent cells respond to mechanical properties of the surrounding extracellular matrix. Mechanical forces, sensed at specialized cell-matrix adhesion…

  Authors: Kristopher Clark, Michiel Langeslag, Carl G Figdor, Frank N van Leeuwen

  Source: Trends in cell biology. 2007 Apr

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• Dendritic cell immunotherapy: mapping the way.

  Dendritic cells (DCs) are the professional antigen-presenting cells of the immune system, with the potential to either stimulate or inhibit immune res…

  Authors: Carl G Figdor, I Jolanda M de Vries, W Joost Lesterhuis, Cornelis J M Melief

  Source: Nature medicine. 2004 May

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• Levels of complexity in pathogen recognition by C-type lectins.

  In pathogen recognition by C-type lectins, several levels of complexity can be distinguished; these might modulate the immune response in different wa…

  Authors: Alessandra Cambi, Carl G Figdor

  Source: Current opinion in immunology. 2005 Aug

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• Dual function of C-type lectin-like receptors in the immune system.

  Carbohydrate-binding C-type lectin and lectin-like receptors play an important role in the immune system. The large family can be subdivided into subt…

  Authors: Alessandra Cambi, Carl G Figdor

  Source: Current opinion in cell biology. 2003 Oct

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• Sweet talk": closing in on C type lectin signaling.

  C type lectins recognize pathogens by binding to pathogen-specific carbohydrate residues. The finding reported by Rogers et al. (2005) in this issue o…

  Authors: Friederike Meyer-Wentrup, Alessandra Cambi, Gosse J Adema, Carl G Figdor

  Source: Immunity. 2005 Apr

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• Migration of dendritic cell based cancer vaccines: in vivo veritas?

  Ex vivo generated cancer vaccines based on dendritic cells (DCs) are currently applied in the clinic. The migration of DCs from the tissues to the lym…

  Authors: Gosse J Adema, I Jolanda M de Vries, Cornelis J A Punt, Carl G Figdor

  Source: Current opinion in immunology. 2005 Apr

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• Targeting DCIR on human plasmacytoid dendritic cells results in antigen presentation and inhibits IFN-alpha production.

  C-type lectin receptors (CLRs) fulfill multiple functions within the immune system by recognition of carbohydrate moieties on foreign or (altered) sel…

  Authors: Friederike Meyer-Wentrup, Daniel Benitez-Ribas, Paul J Tacken, Cornelis J A Punt, Carl G Figdor, I Jolanda M de Vries, Gosse J Adema

  Source: Blood. 2008 Apr 15

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• Different faces of the heme-heme oxygenase system in inflammation.

  The heme-heme oxygenase system has recently been recognized to possess important regulatory properties. It is tightly involved in both physiological a…

  Authors: Frank A D T G Wagener, Hans-Dieter Volk, Dean Willis, Nader G Abraham, Miguel P Soares, Gosse J Adema, Carl G Figdor

  Source: Pharmacological reviews. 2003 Sep

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• In vivo colocalization of antigen and CpG [corrected] within dendritic cells is associated with the efficacy of cancer immunotherapy.

  Immunostimulatory cytidyl guanosyl (CpG) motifs are of great interest as cancer vaccine adjuvants. They act as potent inducers of Th1 responses, inclu…

  Authors: Stefan Nierkens, Martijn H den Brok, Roger P M Sutmuller, Oliver M Grauer, Erik Bennink, Mary E Morgan, Carl G Figdor, Theo J M Ruers, Gosse J Adema

  Source: Cancer research. 2008 Jul 1

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• PGE2-mediated podosome loss in dendritic cells is dependent on actomyosin contraction downstream of the RhoA-Rho-kinase axis.

  Podosomes are dynamic adhesion structures found in dendritic cells (DCs) and other cells of the myeloid lineage. We previously showed that prostagland…

  Authors: Suzanne F G van Helden, Machteld M Oud, Ben Joosten, Niels Peterse, Carl G Figdor, Frank N van Leeuwen

  Source: Journal of cell science. 2008 Apr 1

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