1 to 10 of 400 literature results

• Role of the hypothalamic-pituitary-thyroid axis in metabolic regulation by JNK1.

  The cJun N-terminal kinase 1 (JNK1) is implicated in diet-induced obesity. Indeed, germline ablation of the murine Jnk1 gene prevents diet-induced obe…

  Authors: Guadalupe Sabio, Julie Cavanagh-Kyros, Tamera Barrett, Dae Young Jung, Hwi Jin Ko, Helena Ong, Caroline Morel, Alfonso Mora, Judith Reilly, Jason K Kim,…

  Source: Genes & development. 2010 Feb 1

  View Full Text

• Mcl-1 integrates the opposing actions of signaling pathways that mediate survival and apoptosis.

  Mcl-1 is a member of the Bcl2-related protein family that is a critical mediator of cell survival. Exposure of cells to stress causes inhibition of Mc…

  Authors: Caroline Morel, Scott M Carlson, Forest M White, Roger J Davis

  Source: Molecular and cellular biology. 2009 Jul

  View Free Full Text

• KChIP2 Attenuates Cardiac Hypertrophy Through Regulation of I(to) and Intracellular Calcium Signaling.

  Recent evidence shows that the auxiliary subunit KChIP2, which assembles with pore-forming Kv4-subunits, represents a new potential regulator of the c…

  Authors: Hongwei Jin, Lahouaria Hadri, Julieta Palomeque, Charlotte Morel, Ioannis Karakikes, Roger Kaprielian, Roger Hajjar, Djamel Lebeche

  Source: Journal of molecular and cellular cardiology. 2010 Jan 2

  View Full Text

• Regulation of excision of integrative and potentially conjugative elements from Streptococcus thermophilus: role of the arp1 repressor.

  The integrative and conjugative elements (ICEs) excise by site-specific recombination between attL and attR flanking sites, self-transfer the resultin…

  Authors: Xavier Bellanger, Catherine Morel, Bernard Decaris, Gérard Guédon

  Source: Journal of molecular microbiology and biotechnology. 2008

  View Full Text

• Derepression of excision of integrative and potentially conjugative elements from Streptococcus thermophilus by DNA damage response: implication of a cI-related repressor.

  A DNA-damaging agent, mitomycin C, derepresses the site-specific excision of two integrative and potentially conjugative elements from Streptococcus t…

  Authors: Xavier Bellanger, Catherine Morel, Bernard Decaris, Gérard Guédon

  Source: Journal of bacteriology. 2007 Feb

  View Free Full Text

• Conjugative transfer of the integrative conjugative elements ICESt1 and ICESt3 from Streptococcus thermophilus.

  Integrative and conjugative elements (ICEs), also called conjugative transposons, are genomic islands that excise, self-transfer by conjugation, and i…

  Authors: Xavier Bellanger, Adam P Roberts, Catherine Morel, Frédéric Choulet, Guillaume Pavlovic, Peter Mullany, Bernard Decaris, Gérard Guédon

  Source: Journal of bacteriology. 2009 Apr

  View Free Full Text

• Desirability-based methods of multiobjective optimization and ranking for global QSAR studies. Filtering safe and potent drug candidates from combinatorial libraries.

  Up to now, very few applications of multiobjective optimization (MOOP) techniques to quantitative structure-activity relationship (QSAR) studies have …

  Authors: Maykel Cruz-Monteagudo, Fernanda Borges, M Natália D S Cordeiro, J Luis Cagide Fajin, Carlos Morell, Reinaldo Molina Ruiz, Yudith Cañizares-Carmenate, Elena Rosa Dominguez

  Source: Journal of combinatorial chemistry. 2008 Nov-Dec

  View Full Text

• Involvement of sulfhydryl oxidase QSOX1 in the protection of cells against oxidative stress-induced apoptosis.

  The QSOX1 protein, belonging to a new class of FAD-linked Quiescin/Sulfhydryl oxidase, catalyzes disulfide bond formation. To give new insight into th…

  Authors: Carole Morel, Pascale Adami, Jean-François Musard, Dominique Duval, Jean Radom, Michèle Jouvenot

  Source: Experimental cell research. 2007 Nov 15

  View Full Text

• Imaging performance of the hybrid pixel detectors XPAD3-S.

  Hybrid pixel detectors, originally developed for tracking particles in high-energy physics experiments, have recently been used in material sciences a…

  Authors: F Cassol Brunner, J C Clemens, C Hemmer, C Morel

  Source: Physics in medicine and biology. 2009 Mar 21

  View Full Text

• Mycobacterium bovis BCG-infected neutrophils and dendritic cells cooperate to induce specific T cell responses in humans and mice.

  Neutrophils are increasingly thought to modulate dendritic cell (DC) functions. We investigated the role of the neutrophil-DC partnership in the respo…

  Authors: Céline Morel, Edgar Badell, Valérie Abadie, Macarena Robledo, Niclas Setterblad, Jean Claude Gluckman, Brigitte Gicquel, Sarah Boudaly, Nathalie Winter

  Source: European journal of immunology. 2008 Feb

  View Full Text