1 to 7 of 7 literature results

• Perspective-- FcRn transports albumin: relevance to immunology and medicine.

  Recent evidence validates a forgotten 40-year-old hypothesis: the MHC-related Fc receptor for IgG (FcRn) protects albumin from intracellular catabolic…

  Authors: Clark L Anderson, Chaity Chaudhury, Jonghan Kim, C L Bronson, Manzoor A Wani, Sudhasri Mohanty

  Source: Trends in immunology. 2006 Jul

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• Beta 2-microglobulin deficient mice catabolize IgG more rapidly than FcRn- alpha-chain deficient mice.

  FcRn, a nonclassical MHC-I protein bound to beta 2-microglobulin (beta 2m), diverts IgG and albumin from an intracellular degradative fate, prolonging…

  Authors: Jonghan Kim, C L Bronson, Manzoor A Wani, Tatiana M Oberyszyn, Sudhasri Mohanty, Chaity Chaudhury, William L Hayton, John M Robinson, Clark L Anderson

  Source: Experimental biology and medicine (Maywood, N.J.). 2008 May

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• Albumin turnover: FcRn-mediated recycling saves as much albumin from degradation as the liver produces.

  It is now understood that the nonclassical major histocompatibility complex-I molecule FcRn binds albumin and retrieves it from an intracellular degra…

  Authors: Jonghan Kim, C L Bronson, William L Hayton, Michael D Radmacher, Derry C Roopenian, John M Robinson, Clark L Anderson

  Source: American journal of physiology. Gastrointestinal and liver physiology. 2006 Feb

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• A test of the endogenous and exogenous selection hypotheses for the maintenance of a narrow avian hybrid zone.

  The contributions of genetic and environmental factors to differential reproductive success across hybrid zones have rarely been tested. Here, we repo…

  Authors: C L Bronson, Thomas C Grubb, Michael J Braun

  Source: Evolution; international journal of organic evolution. 2003 Mar

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• Accelerated transferrin degradation in HFE-deficient mice is associated with increased transferrin saturation.

  HFE, a major histocompatibility complex class I-related protein, is implicated in the iron overload disease, hereditary hemochromatosis. Whereas patie…

  Authors: Chaity Chaudhury, Jonghan Kim, Samina Mehnaz, Manzoor A Wani, Tatiana M Oberyszyn, C L Bronson, Sudhasri Mohanty, William L Hayton, John M Robinson, Clark L Anderson

  Source: The Journal of nutrition. 2006 Dec

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• Familial hypercatabolic hypoproteinemia caused by deficiency of the neonatal Fc receptor, FcRn, due to a mutant beta2-microglobulin gene.

  Two siblings, products of a consanguineous marriage, were markedly deficient in both albumin and IgG because of rapid degradation of these proteins, s…

  Authors: Manzoor A Wani, Lynn D Haynes, Jonghan Kim, C L Bronson, Chaity Chaudhury, Sudhasri Mohanty, Thomas A Waldmann, John M Robinson, Clark L Anderson

  Source: Proceedings of the National Academy of Sciences of the United States of America. 2006 Mar 28

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• Database design for an archive of animal sounds.

  Authors: D A Nelson, S L Gaunt, C L Bronson, T J Kloth

  Source: IEEE engineering in medicine and biology magazine : the quarterly magazine of the Engineering in Medicine & Biology Society. 2001 May-Jun

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