Click on one of these terms to refine your search
1 to 10 of 37 literature results
-
ETS rearrangements and prostate cancer initiation.
The first recurrent translocation event in prostate cancer has been recently described; it results in the translocation of an ETS (E26 transformation …
Authors: Brett S Carver, Jennifer Tran, Zhenbang Chen, Arkaitz Carracedo-Perez, Andrea Alimonti, Caterina Nardella, Anuradha Gopalan, Peter T Scardino, Carlos Cordon-Cardo, William Gerald,…
Source: Nature. 2009 Feb 12
View Full Text -
Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis.
The TMPRSS2-ERG fusion, present in approximately 50% of prostate cancers, is less common in prostatic intraepithelial neoplasia (PIN), raising questio…
Authors: Jennifer C King, Jin Xu, John Wongvipat, Haley Hieronymus, Brett S Carver, David H Leung, Barry S Taylor, Chris Sander, Robert D Cardiff, Suzana S Couto,…
Source: Nature genetics. 2009 May
View Full Text -
Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate.
Chromosomal translocations involving the ERG locus are frequent events in human prostate cancer pathogenesis; however, the biological role of aberrant…
Authors: Brett S Carver, Jennifer Tran, Anuradha Gopalan, Zhenbang Chen, Safa Shaikh, Arkaitz Carracedo, Andrea Alimonti, Caterina Nardella, Shohreh Varmeh, Peter T Scardino,…
Source: Nature genetics. 2009 May
View Full Text -
Ubiquitination regulates PTEN nuclear import and tumor suppression.
The PTEN tumor suppressor is frequently affected in cancer cells, and inherited PTEN mutation causes cancer-susceptibility conditions such as Cowden s…
Authors: Lloyd C Trotman, Xinjiang Wang, Andrea Alimonti, Zhenbang Chen, Julie Teruya-Feldstein, Haijuan Yang, Nikola P Pavletich, Brett S Carver, Carlos Cordon-Cardo, Hediye Erdjument-Bromage,…
Source: Cell. 2007 Jan 12
View Free Full Text -
Management of post-chemotherapy extra-retroperitoneal residual masses.
INTRODUCTION: Testicular cancer is the most common cancer in men age 20-35 years and accounts for approximately 1% of all male malignancies. While the…
Authors: Brett S Carver, Joel Sheinfeld
Source: World journal of urology. 2009 Aug
View Full Text -
The indication for postchemotherapy lymph node dissection in clinical stage IS nonseminomatous germ cell tumor.
BACKGROUND: The initial management of patients with clinical stage IS (cIS) nonseminomatous germ cell tumor (NSGCT) has evolved from primary retroperi…
Authors: Atreya Dash, Brett S Carver, Jason Stasi, Dean F Bajorin, Robert J Motzer, George J Bosl, Joel Sheinfeld
Source: Cancer. 2008 Feb 15
View Full Text -
Preservation of ejaculation in patients undergoing nerve-sparing postchemotherapy retroperitoneal lymph node dissection for metastatic testicular cancer.
OBJECTIVES: To evaluate the clinical parameters associated with the recovery of ejaculation after nerve-sparing postchemotherapy retroperitoneal lymph…
Authors: Joseph A Pettus, Brett S Carver, Timothy Masterson, Jason Stasi, Joel Sheinfeld
Source: Urology. 2009 Feb
View Full Text -
Pathologic findings and clinical outcome of patients undergoing retroperitoneal lymph node dissection after multiple chemotherapy regimens for metastatic testicular germ cell tumors.
BACKGROUND: Postchemotherapy surgery is an essential component in the management of patients with metastatic germ cell tumors (GCT). The authors asses…
Authors: Scott E Eggener, Brett S Carver, Stacy Loeb, G Varuni Kondagunta, George J Bosl, Joel Sheinfeld
Source: Cancer. 2007 Feb 1
View Full Text -
Germ cell tumors of the testis.
Testicular cancer is the most common malignancy in men aged 20 to 35 years and accounts for approximately 1% of all male malignancies. Through the app…
Authors: Brett S Carver, Joel Sheinfeld
Source: Annals of surgical oncology. 2005 Nov
View Full Text -
Secondary therapy, metastatic progression, and cancer-specific mortality in men with clinically high-risk prostate cancer treated with radical prostatectomy.
OBJECTIVES: Commonly used definitions for high-risk prostate cancer identify men at increased risk of PSA relapse after radical prostatectomy (RP). We…
Authors: Ofer Yossepowitch, Scott E Eggener, Angel M Serio, Brett S Carver, Fernando J Bianco, Peter T Scardino, James A Eastham
Source: European urology. 2008 May
View Free Full Text
