1 to 10 of 32 literature results

• Inhibitory killer Ig-like receptor genes and human leukocyte antigen class I ligands in haematopoietic stem cell transplantation.

  Identification of inhibitory killer Ig-like receptor (KIR) genes and their cognate human leukocyte antigen (HLA) class I ligands in donor-recipient pa…

  Authors: Bo Dupont, Katharine C Hsu

  Source: Current opinion in immunology. 2004 Oct

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• Improved outcome in HLA-identical sibling hematopoietic stem-cell transplantation for acute myelogenous leukemia predicted by KIR and HLA genotypes.

  Inhibitory killer immunoglobulin (Ig)-like receptors (KIRs) recognize HLA-C and -B epitopes on target cells, thereby regulating natural killer (NK) ce…

  Authors: Katharine C Hsu, Carolyn A Keever-Taylor, Andrew Wilton, Clara Pinto, Glenn Heller, Knarik Arkun, Richard J O'Reilly, Mary M Horowitz, Bo Dupont

  Source: Blood. 2005 Jun 15

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• Natural killer cell receptors: regulating innate immune responses to hematologic malignancy.

  Critical to innate immunity, the natural killer (NK) cell performs its function of immunosurveillance through its recognition of altered or missing se…

  Authors: Katharine C Hsu, Bo Dupont

  Source: Seminars in hematology. 2005 Apr

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• Visualization of signaling pathways and cortical cytoskeleton in cytolytic and noncytolytic natural killer cell immune synapses.

  Recent applications of imaging approaches and other methods of cell biology have provided high-resolution visualization of the location of fluorescent…

  Authors: Yatin M Vyas, Hina Maniar, Bo Dupont

  Source: Immunological reviews. 2002 Nov

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• The killer cell immunoglobulin-like receptor (KIR) genomic region: gene-order, haplotypes and allelic polymorphism.

  Recent genetic studies have established that the killer cell immunoglobulin-like receptor (KIR) genomic region displays extensive diversity through va…

  Authors: Katharine C Hsu, Shohei Chida, Daniel E Geraghty, Bo Dupont

  Source: Immunological reviews. 2002 Dec

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• Quantitation, selection, and functional characterization of Epstein-Barr virus-specific and alloreactive T cells detected by intracellular interferon-gamma production and growth of cytotoxic precursors.

  Techniques for the quantitation of virus-specific and alloantigen-reactive T cells vary in their measurement of clinically relevant T-cell effector po…

  Authors: Guenther Koehne, Katherine M Smith, Teresa L Ferguson, Roxanne Y Williams, Glenn Heller, Eric G Pamer, Bo Dupont, Richard J O'Reilly

  Source: Blood. 2002 Mar 1

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• Infusion of haplo-identical killer immunoglobulin-like receptor ligand mismatched NK cells for relapsed myeloma in the setting of autologous stem cell transplantation.

  Killer immunoglobulin-like receptor (KIR)-ligand mismatched natural killer (NK) cells play a key role in achieving durable remission after haplo-ident…

  Authors: Jumei Shi, Guido Tricot, Susann Szmania, Nancy Rosen, Tarun K Garg, Priyangi A Malaviarachchi, Amberly Moreno, Bo Dupont, Katharine C Hsu, Lee Ann Baxter-Lowe,…

  Source: British journal of haematology. 2008 Dec

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• Introduction: current concepts in immunity to human cancer and therapeutic antitumor vaccines.

  Authors: Bo Dupont

  Source: Immunological reviews. 2002 Oct

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• The lytic potential of human liver NK cells is restricted by their limited expression of inhibitory killer Ig-like receptors.

  The human liver is enriched in NK cells which are potent effectors of the innate immune system. We have determined that liver NK cells freshly isolate…

  Authors: Bryan M Burt, George Plitas, Zeguo Zhao, Zubin M Bamboat, Hoang M Nguyen, Bo Dupont, Ronald P DeMatteo

  Source: Journal of immunology (Baltimore, Md. : 1950). 2009 Aug 1

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• KIR and HLA genotypes are associated with disease progression and survival following autologous hematopoietic stem cell transplantation for high-risk neuroblastoma.

  PURPOSE: NK cells exhibit cytotoxicity against neuroblastoma. Gene polymorphisms governing NK cell function, therefore, may influence prognosis. Two h…

  Authors: Jeffrey M Venstrom, Junting Zheng, Nabila Noor, Karen E Danis, Alice W Yeh, Irene Y Cheung, Bo Dupont, Richard J O'Reilly, Nai-Kong V Cheung, Katharine C Hsu

  Source: Clinical cancer research : an official journal of the American Association for Cancer Research. 2009 Dec 1

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