1 to 9 of 9 literature results

• Photoacoustic tomography of carrageenan-induced arthritis in a rat model.

  Laser-based photoacoustic tomography (PAT), a novel, nonionizing, noninvasive, laser-based technology, has been adapted to the diagnosis and imaging o…

  Authors: David L Chamberland, Xueding Wang, Blake J Roessler

  Source: Journal of biomedical optics. 2008 Jan-Feb

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• Raman spectroscopy of synovial fluid as a tool for diagnosing osteoarthritis.

  For many years, viscosity has been the primary method used by researchers in rheumatology to assess the physiochemical properties of synovial fluid in…

  Authors: Karen A Esmonde-White, Gurjit S Mandair, Farhang Raaii, Jon A Jacobson, Bruce S Miller, Andrew G Urquhart, Blake J Roessler, Michael D Morris

  Source: Journal of biomedical optics. 2009 May-Jun

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• Effect of conformation and drop properties on surface-enhanced Raman spectroscopy of dried biopolymer drops.

  Biofluids are complex solutions consisting of small ions and large biopolymers such as DNA, proteins, or proteoglycans. Biopolymers affect fluid prope…

  Authors: Karen A Esmonde-White, Stephanie V Le Clair, Blake J Roessler, Michael D Morris

  Source: Applied spectroscopy. 2008 May

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• Imaging of joints with laser-based photoacoustic tomography: an animal study.

  Photoacoustic tomography (PAT), a nonionizing, noninvasive, laser-based technology was adapted to joint imaging for the first time. Pulsed laser light…

  Authors: Xueding Wang, David L Chamberland, Paul L Carson, J Brian Fowlkes, Ronald O Bude, David A Jamadar, Blake J Roessler

  Source: Medical physics. 2006 Aug

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• Correlating changes in collagen secondary structure with aging and defective type II collagen by Raman spectroscopy.

  A novel application of Raman spectroscopy for monitoring damage to ocular collagen in wild-type mice and Del1 (+/-) transgenic mice, a murine animal m…

  Authors: Karen A Dehring, Abigail R Smukler, Blake J Roessler, Michael D Morris

  Source: Applied spectroscopy. 2006 Apr

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• Identifying chemical changes in subchondral bone taken from murine knee joints using Raman spectroscopy.

  Application of Raman spectroscopy to analysis of subchondral bone is described. The effect of cartilage health on subchondral bone has been widely stu…

  Authors: Karen A Dehring, Nicole J Crane, Abigail R Smukler, Jonathan B McHugh, Blake J Roessler, Michael D Morris

  Source: Applied spectroscopy. 2006 Oct

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• Bile acid-oligopeptide conjugates interact with DNA and facilitate transfection.

  Bile acids conjugated to oligoarginine-containing peptides (BACs) form complexes with DNA based on the electrostatic interactions between negatively c…

  Authors: Phillip E Kish, Yasuhiro Tsume, Paul Kijek, Thomas M Lanigan, John M Hilfinger, Blake J Roessler

  Source: Molecular pharmaceutics. 2007 Jan-Feb

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• Lipopolysaccharide recognition protein, MD-2, facilitates cellular uptake of E. coli-derived plasmid DNA in synovium.

  BACKGROUND: Several cell types are susceptible to transfection in vivo using naked plasmid DNA. The mechanisms involved in mediating in vivo transfect…

  Authors: Jacquelyn A Kolka, Andrew P Vreede, Blake J Roessler

  Source: The journal of gene medicine. 2005 Jul

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• Adenovirus binding to cultured synoviocytes triggers signaling through MAPK pathways and induces expression of cyclooxygenase-2.

  BACKGROUND: Recombinant adenovirus can be administered in vivo to achieve transduction of a number of cell types including human synoviocytes. Immunog…

  Authors: Leslie J Crofford, Kevin T McDonagh, Sutang Guo, Hemal Mehta, Huimin Bian, Lilli M Petruzelli, Blake J Roessler

  Source: The journal of gene medicine. 2005 Mar

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