1 to 3 of 3 literature results

• Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers.

  Basal-like breast cancers arising in women carrying mutations in the BRCA1 gene, encoding the tumor suppressor protein BRCA1, are thought to develop f…

  Authors: Elgene Lim, François Vaillant, Di Wu, Natasha C Forrest, Bhupinder Pal, Adam H Hart, Marie-Liesse Asselin-Labat, David E Gyorki, Teresa Ward, Audrey Partanen,…

  Source: Nature medicine. 2009 Aug

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• SCFCdc4-mediated degradation of the Hac1p transcription factor regulates the unfolded protein response in Saccharomyces cerevisiae.

  The Saccharomyces cerevisiae basic leucine zipper transcription factor Hac1p is synthesized in response to the accumulation of unfolded polypeptides i…

  Authors: Bhupinder Pal, Nickie C Chan, Leon Helfenbaum, Kaeling Tan, William P Tansey, Mary-Jane Gething

  Source: Molecular biology of the cell. 2007 Feb

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• Notch signaling regulates mammary stem cell function and luminal cell-fate commitment.

  The recent identification of mouse mammary stem cells (MaSCs) and progenitor subpopulations has enhanced the prospect of investigating the genetic con…

  Authors: Toula Bouras, Bhupinder Pal, François Vaillant, Gwyndolen Harburg, Marie-Liesse Asselin-Labat, Samantha R Oakes, Geoffrey J Lindeman, Jane E Visvader

  Source: Cell stem cell. 2008 Oct 9

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