1 to 10 of 59 literature results

• Neurotoxic autoantibodies mediate congenital cortical impairment of offspring in maternal lupus.

  Systemic lupus erythematosus (SLE) is an autoimmune disease mediated by autoantibodies and preferentially affecting women of childbearing age. Because…

  Authors: Ji Y Lee, Patricio T Huerta, Jie Zhang, Czeslawa Kowal, Eva Bertini, Bruce T Volpe, Betty Diamond

  Source: Nature medicine. 2009 Jan

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• Cognition and immunity; antibody impairs memory.

  Patients with lupus (SLE) experience progressive cognitive loss without evidence of CNS vascular disease or inflammation. SLE patients produce anti-DN…

  Authors: Czeslawa Kowal, Lorraine A DeGiorgio, Tsukasa Nakaoka, Hoby Hetherington, Patricio T Huerta, Betty Diamond, Bruce T Volpe

  Source: Immunity. 2004 Aug

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• Activated memory B cell subsets correlate with disease activity in systemic lupus erythematosus: delineation by expression of CD27, IgD, and CD95.

  OBJECTIVE: Analysis of peripheral B cell subsets in patients with systemic lupus erythematosus (SLE) has provided evidence of specific alterations, su…

  Authors: Annett M Jacobi, Karin Reiter, Meggan Mackay, Cynthia Aranow, Falk Hiepe, Andreas Radbruch, Arne Hansen, Gerd-R Burmester, Betty Diamond, Peter E Lipsky,…

  Source: Arthritis and rheumatism. 2008 Jun

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• ICER/CREM-mediated transcriptional attenuation of IL-2 and its role in suppression by regulatory T cells.

  Here, we report that inducible cAMP early repressor/cAMP response element modulator (ICER/CREM) is induced early in CD25(+)CD4(+) regulatory T cell (T…

  Authors: Josef Bodor, Zoltan Fehervari, Betty Diamond, Shimon Sakaguchi

  Source: European journal of immunology. 2007 Apr

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• Regulatory T cell-mediated suppression: potential role of ICER.

  How regulatory T (TR) cells dampen T cell responses remains unclear. Multiple modes of action have been proposed, including cell contact-dependent and…

  Authors: Josef Bodor, Zoltan Fehervari, Betty Diamond, Shimon Sakaguchi

  Source: Journal of leukocyte biology. 2007 Jan

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• Autoantibodies that bind glomeruli: cross-reactivity with bacterial antigen.

  OBJECTIVE: Systemic lupus erythematosus (SLE) is characterized by the production of multiple autoantibodies. Anti-DNA antibodies are associated with g…

  Authors: Iftikhar A Chowdhry, Czeslawa Kowal, John Hardin, Zhijie Zhou, Betty Diamond

  Source: Arthritis and rheumatism. 2005 Aug

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• Generation and maturation of bone marrow-derived DCs under serum-free conditions.

  Standard protocols for the generation of murine dendritic cells (DCs) employ medium supplemented with heat-inactivated fetal calf serum (FCS). Recentl…

  Authors: Sung Jung Kim, Betty Diamond

  Source: Journal of immunological methods. 2007 Jun 30

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• Immunity and acquired alterations in cognition and emotion: lessons from SLE.

  Classic immunologic teaching describes the brain as an immunologically privileged site. Studies of neuroimmunology have focused for many years almost …

  Authors: Betty Diamond, Czeslawa Kowal, Patricio T Huerta, Cynthia Aranow, Meggan Mackay, Lorraine A DeGiorgio, Ji Lee, Antigone Triantafyllopoulou, Joel Cohen-Solal, Bruce T Volpe

  Source: Advances in immunology. 2006

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• Human recombinant Fab fragments with sub-nanomolar affinities for acetylated histones.

  Acetylation of lysines at different sites in the N-terminus of core histones is a common mode of chromatin modification; different combinations of suc…

  Authors: Iglika Batova, Czeslawa Kowal, Rena May, Matthew D Scharff, Betty Diamond

  Source: Journal of immunological methods. 2008 Jan 1

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• The effect of moderate-dose corticosteroids in preventing severe flares in patients with serologically active, but clinically stable, systemic lupus erythematosus: findings of a prospective, randomized, double-blind, placebo-controlled trial.

  OBJECTIVE: Serial measurements of anti-double-stranded DNA (anti-dsDNA) and complement are routine in the management of systemic lupus erythematosus (…

  Authors: Chung-E Tseng, Jill P Buyon, Mimi Kim, H Michael Belmont, Meggan Mackay, Betty Diamond, Galina Marder, Pamela Rosenthal, Kathleen Haines, Virginia Ilie,…

  Source: Arthritis and rheumatism. 2006 Nov

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