1 to 10 of 58 literature results

• Methods in mammalian autophagy research.

  Autophagy has been implicated in many physiological and pathological processes. Accordingly, there is a growing scientific need to accurately identify…

  Authors: Noboru Mizushima, Tamotsu Yoshimori, Beth Levine

  Source: Cell. 2010 Feb 5

  View Full Text

• Autophagy genes in immunity.

  In its classical form, autophagy is a pathway by which cytoplasmic constituents, including intracellular pathogens, are sequestered in a double-membra…

  Authors: Herbert W Virgin, Beth Levine

  Source: Nature immunology. 2009 May

  View Full Text

• Autophagy in the pathogenesis of disease.

  Autophagy is a lysosomal degradation pathway that is essential for survival, differentiation, development, and homeostasis. Autophagy principally serv…

  Authors: Beth Levine, Guido Kroemer

  Source: Cell. 2008 Jan 11

  View Free Full Text

• Eating oneself and uninvited guests: autophagy-related pathways in cellular defense.

  The eukaryotic cell uses an evolutionarily conserved lysosomal pathway of self-digestion (autophagy) for survival when extracellular nutrients are lim…

  Authors: Beth Levine

  Source: Cell. 2005 Jan 28

  View Full Text

• p53: The Janus of autophagy?

  The autophagy pathway functions in adaptation to nutrient stress and tumour suppression. The p53 tumour suppressor, previously thought to positively r…

  Authors: Beth Levine, John Abrams

  Source: Nature cell biology. 2008 Jun

  View Free Full Text

• Autophagy fights disease through cellular self-digestion.

  Autophagy, or cellular self-digestion, is a cellular pathway involved in protein and organelle degradation, with an astonishing number of connections …

  Authors: Noboru Mizushima, Beth Levine, Ana Maria Cuervo, Daniel J Klionsky

  Source: Nature. 2008 Feb 28

  View Free Full Text

• The role of autophagy in mammalian development: cell makeover rather than cell death.

  Autophagy is important for the degradation of bulk cytoplasm, long-lived proteins, and entire organelles. In lower eukaryotes, autophagy functions as …

  Authors: Francesco Cecconi, Beth Levine

  Source: Developmental cell. 2008 Sep

  View Free Full Text

• JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy.

  Starvation induces autophagy to preserve cellular homeostasis in virtually all eukaryotic organisms. However, the mechanisms by which starvation induc…

  Authors: Yongjie Wei, Sophie Pattingre, Sangita Sinha, Michael Bassik, Beth Levine

  Source: Molecular cell. 2008 Jun 20

  View Free Full Text

• Autophagy gene-dependent clearance of apoptotic cells during embryonic development.

  Autophagy is commonly observed in metazoan organisms during programmed cell death (PCD), but its function in dying cells has been unclear. We studied …

  Authors: Xueping Qu, Zhongju Zou, Qihua Sun, Kate Luby-Phelps, Pengfei Cheng, Robert N Hogan, Christopher Gilpin, Beth Levine

  Source: Cell. 2007 Mar 9

  View Full Text

• Cell biology: autophagy and cancer.

  Authors: Beth Levine

  Source: Nature. 2007 Apr 12

  View Full Text