1 to 7 of 7 literature results

• Multifactorial analysis of predictors of outcome in pediatric intracranial ependymoma.

  Pediatric ependymomas are enigmatic tumors, and their clinical management remains one of the more difficult in pediatric oncology. The identification …

  Authors: Lee Ridley, Ruman Rahman, Marie-Anne Brundler, David Ellison, James Lowe, Keith Robson, Emma Prebble, Inga Luckett, Richard J Gilbertson, Sheila Parkes,…

  Source: Neuro-oncology. 2008 Oct

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• Early drug safety evaluation: biomarkers, signatures, and fingerprints.

  When target organ toxicity arises in animal models during routine drug safety evaluation, it raises several key questions: Is this target organ toxici…

  Authors: Ruth Roberts, Kelvin Cain, Beth Coyle, Caroline Freathy, Jean-Francois Leonard, Jean-Charles Gautier

  Source: Drug metabolism reviews. 2003 Nov

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• Regulation of apoptosis by peroxisome proliferators.

  Peroxisome proliferators (PPs) constitute a large and chemically diverse family of non-genotoxic rodent hepatocarcinogens that activate the PP-activat…

  Authors: Ruth A Roberts, Cecile Michel, Beth Coyle, Caroline Freathy, Kelvin Cain, Eric Boitier

  Source: Toxicology letters. 2004 Apr 1

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• Novel strategy to study gene expression and function in developing cerebellar granule cells.

  The advent of techniques for global analyses of cell biology, such as genomics and proteomics, opens the way to rapid progress in understanding the mo…

  Authors: Zeng-jie Yang, Vanessa J Appleby, Beth Coyle, Wai-In Chan, Mohammad Tahmaseb, Peter M Wigmore, Paul J Scotting

  Source: Journal of neuroscience methods. 2004 Jan 30

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• Pediatric ependymoma: biological perspectives.

  Pediatric ependymomas are enigmatic tumors that continue to present a clinical management challenge despite advances in neurosurgery, neuroimaging tec…

  Authors: John-Paul Kilday, Ruman Rahman, Sara Dyer, Lee Ridley, James Lowe, Beth Coyle, Richard Grundy

  Source: Molecular cancer research : MCR. 2009 Jun

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• Strategies to investigate gene expression and function in granule cells.

  Studying gene expression in granule cells is a major route to understanding the factors required for many key cellular processes such as specification…

  Authors: Rebecca M Savill, Paul J Scotting, Beth Coyle

  Source: Cerebellum (London, England). 2005

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• Characterization of the transforming growth factor-beta 1-induced apoptotic transcriptome in FaO hepatoma cells.

  We have previously shown that transforming growth factor-beta(1) (TGF-beta(1))-induced apoptosis in FaO hepatoma cells is mediated by cytochrome c rel…

  Authors: Beth Coyle, Caroline Freathy, Timothy W Gant, Ruth A Roberts, Kelvin Cain

  Source: The Journal of biological chemistry. 2003 Feb 21

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