1 to 10 of 41 literature results

• Nrf2-deficient mice have an increased susceptibility to dextran sulfate sodium-induced colitis.

  Inflammatory bowel diseases, chronic inflammatory disorders, have been strongly linked with an increased risk of the development of colorectal cancer.…

  Authors: Tin Oo Khor, Mou-Tuan Huang, Ki Han Kwon, Jefferson Y Chan, Bandaru S Reddy, Ah-Ng Kong

  Source: Cancer research. 2006 Dec 15

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• Prevention of colon cancer by low doses of celecoxib, a cyclooxygenase inhibitor, administered in diet rich in omega-3 polyunsaturated fatty acids.

  Epidemiologic and animal studies suggest that a high-fat diet containing mixed lipids promotes colorectal cancer, whereas fish oil lacks promoting eff…

  Authors: Bandaru S Reddy, Jagan M Patlolla, Barbara Simi, S H Wang, Chinthalapally V Rao

  Source: Cancer research. 2005 Sep 1

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• Chemoprevention of familial adenomatous polyposis by low doses of atorvastatin and celecoxib given individually and in combination to APCMin mice.

  Preclinical and clinical studies have established evidence that cyclooxygenase-2 (COX-2) inhibitors and statins [hydroxy-3-methylglutaryl CoA reductas…

  Authors: Malisetty V Swamy, Jagan M R Patlolla, Vernon E Steele, Levy Kopelovich, Bandaru S Reddy, Chinthalapally V Rao

  Source: Cancer research. 2006 Jul 15

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• Chemoprevention of familial adenomatous polyposis by natural dietary compounds sulforaphane and dibenzoylmethane alone and in combination in ApcMin/+ mouse.

  Cancer chemopreventive agent sulforaphane (SFN) and dibenzoylmethane (DBM) showed antitumorigenesis effects in several rodent carcinogenesis models. I…

  Authors: Guoxiang Shen, Tin Oo Khor, Rong Hu, Siwang Yu, Sujit Nair, Chi-Tang Ho, Bandaru S Reddy, Mou-Tuan Huang, Harold L Newmark, Ah-Ng Tony Kong

  Source: Cancer research. 2007 Oct 15

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• Prevention of azoxymethane-induced colon cancer by combination of low doses of atorvastatin, aspirin, and celecoxib in F 344 rats.

  Preclinical and clinical studies have provided evidence that aspirin, celecoxib, (cyclooxygenase-2 inhibitor), and statins (3-hydroxy-3-methylglutaryl…

  Authors: Bandaru S Reddy, Chung Xiou Wang, Ah-Ng Kong, Tin Oo Khor, Xi Zheng, Vernon E Steele, Levy Kopelovich, Chinthalapally V Rao

  Source: Cancer research. 2006 Apr 15

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• Green tea polyphenols inhibit colorectal aberrant crypt foci (ACF) formation and prevent oncogenic changes in dysplastic ACF in azoxymethane-treated F344 rats.

  Green tea and its constituents have shown cancer-preventive activities in many animal models. In order to prepare for a human trial on the inhibition …

  Authors: Hang Xiao, Xingpei Hao, Barbara Simi, Jihyeung Ju, Heyuan Jiang, Bandaru S Reddy, Chung S Yang

  Source: Carcinogenesis. 2008 Jan

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• Chemoprevention of familial adenomatous polyposis in Apc(Min/+) mice by phenethyl isothiocyanate (PEITC).

  Phenethyl isothiocyanate (PEITC) is an isothiocyanate which is a major constituent of watercress and other cruciferous vegetables. Its chemopreventive…

  Authors: Tin Oo Khor, William Ka Lung Cheung, Auemduan Prawan, Bandaru S Reddy, Ah-Ng Tony Kong

  Source: Molecular carcinogenesis. 2008 May

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• Modulation of inducible nitric oxide synthase and related proinflammatory genes by the omega-3 fatty acid docosahexaenoic acid in human colon cancer cells.

  Epidemiological and preclinical studies demonstrate that consumption of diets high in omega-3 polyunsaturated fatty acids reduces the risk of colon ca…

  Authors: Bhagavathi A Narayanan, Narayanan K Narayanan, Barbara Simi, Bandaru S Reddy

  Source: Cancer research. 2003 Mar 1

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• Studies with the azoxymethane-rat preclinical model for assessing colon tumor development and chemoprevention.

  During recent years, multidisciplinary studies in epidemiology and molecular biology have contributed to our understanding of the etiology of colorect…

  Authors: Bandaru S Reddy

  Source: Environmental and molecular mutagenesis. 2004

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• Chemopreventive properties of a selective inducible nitric oxide synthase inhibitor in colon carcinogenesis, administered alone or in combination with celecoxib, a selective cyclooxygenase-2 inhibitor.

  The inducible isoforms of nitric oxide synthase (iNOS) and cyclooxygenase (COX-2) are overexpressed in colonic tumors of humans, as well as in colon t…

  Authors: Chinthalapally V Rao, Cooma Indranie, Barbara Simi, Pamela T Manning, Jane R Connor, Bandaru S Reddy

  Source: Cancer research. 2002 Jan 1

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