1 to 3 of 3 literature results

• Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms.

  Acquired uniparental disomy (aUPD) is a common feature of cancer genomes, leading to loss of heterozygosity. aUPD is associated not only with loss-of-…

  Authors: Masashi Sanada, Takahiro Suzuki, Lee-Yung Shih, Makoto Otsu, Motohiro Kato, Satoshi Yamazaki, Azusa Tamura, Hiroaki Honda, Mamiko Sakata-Yanagimoto, Keiki Kumano,…

  Source: Nature. 2009 Aug 13

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• Frequent inactivation of A20 in B-cell lymphomas.

  A20 is a negative regulator of the NF-kappaB pathway and was initially identified as being rapidly induced after tumour-necrosis factor-alpha stimulat…

  Authors: Motohiro Kato, Masashi Sanada, Itaru Kato, Yasuharu Sato, Junko Takita, Kengo Takeuchi, Akira Niwa, Yuyan Chen, Kumi Nakazaki, Junko Nomoto,…

  Source: Nature. 2009 Jun 4

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• 1alpha,25-Dihydroxyvitamin D(3)-26,23-lactam analogues function as vitamin D receptor antagonists in human and rodent cells.

  23S,25S)-N-Benzyl-1alpha,25-dihydroxyvitamin D(3)-26,23-lactam ((23S,25S)-N-benzyl-1alpha,25-(OH)(2)D(3)-26,23-lactam, (23S,25S)-DLAM-1P) antagonizes …

  Authors: Seiichi Ishizuka, Noriyoshi Kurihara, Yuko Hiruma, Daishiro Miura, Jun-ichi Namekawa, Azusa Tamura, Yuko Kato-Nakamura, Yusuke Nakano, Kazuya Takenouchi, Yuichi Hashimoto,…

  Source: The Journal of steroid biochemistry and molecular biology. 2008 Jun

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