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• Foxa2-dependent hepatic gene regulatory networks depend on physiological state.

  Bile acids are powerful detergents produced by the liver to aid in the absorption of dietary lipids. We recently reported a novel role for Foxa2 in bi…

  Authors: Irina M Bochkis, Jonathan Schug, Nir E Rubins, Atul R Chopra, Bert W O'Malley, Klaus H Kaestner

  Source: Physiological genomics. 2009 Jul 9

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• Absence of the SRC-2 coactivator results in a glycogenopathy resembling Von Gierke's disease.

  Hepatic glucose production is critical for basal brain function and survival when dietary glucose is unavailable. Glucose-6-phosphatase (G6Pase) is an…

  Authors: Atul R Chopra, Jean-Francois Louet, Pradip Saha, Jie An, Franco Demayo, Jianming Xu, Brian York, Saul Karpen, Milton Finegold, David Moore,…

  Source: Science (New York, N.Y.). 2008 Nov 28

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