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About 25% to 30% of the bacterial proteins function in the cell envelope or outside of the cell. These proteins are synthesized in the cytosol, and th…
Authors: Arnold J M Driessen, Nico Nouwen
Source: Annual review of biochemistry. 2008
View Full TextAuthors: Arnold J M Driessen
Source: Nature. 2005 Nov 17
View Full TextSec translocase catalyzes membrane protein insertion and translocation. We have introduced stretches of charged amino acid residues into the preprotei…
Authors: Nico Nouwen, Greetje Berrelkamp, Arnold J M Driessen
Source: Journal of molecular biology. 2009 Mar 6
View Full TextProtein translocation in Escherichia coli is mediated by the translocase that, in its minimal form, comprises a protein-conducting pore (SecYEG) and a…
Authors: Danuta Tomkiewicz, Nico Nouwen, Arnold J M Driessen
Source: Journal of molecular biology. 2008 Mar 14
View Full TextThe Sec machinery facilitates the translocation of proteins across and into biological membranes. In several of the Proteobacteria, this machinery con…
Authors: Eli O van der Sluis, Arnold J M Driessen
Source: Trends in microbiology. 2006 Mar
View Full TextSs-LrpB is an Lrp-like transcriptional regulator from Sulfolobus solfataricus. Previously, in vitro binding of Ss-LrpB to the control region of its ow…
Authors: Eveline Peeters, Sonja-Verena Albers, Amelia Vassart, Arnold J M Driessen, Daniel Charlier
Source: Molecular microbiology. 2009 Feb
View Full TextIndustrial penicillin production with the filamentous fungus Penicillium chrysogenum is based on an unprecedented effort in microbial strain improveme…
Authors: Marco A van den Berg, Richard Albang, Kaj Albermann, Jonathan H Badger, Jean-Marc Daran, Arnold J M Driessen, Carlos Garcia-Estrada, Natalie D Fedorova, Diana M Harris, Wilbert H M Heijne,…
Source: Nature biotechnology. 2008 Oct
View Full TextIt is generally assumed that preprotein substrates must be presented in an unfolded state to the bacterial Sec-translocase in order to be translocated…
Authors: Nico Nouwen, Greetje Berrelkamp, Arnold J M Driessen
Source: Journal of molecular biology. 2007 Sep 14
View Full TextAttachment of microorganisms to surfaces is a prerequisite for colonization and biofilm formation. The hyperthermophilic crenarchaeote Sulfolobus solf…
Authors: Behnam Zolghadr, Andreas Klingl, Andrea Koerdt, Arnold J M Driessen, Reinhard Rachel, Sonja-Verena Albers
Source: Journal of bacteriology. 2010 Jan
View Full TextThe insertion of inner membrane proteins in Escherichia coli occurs almost exclusively via the SecYEG pathway, while some membrane proteins require th…
Authors: Stefan Kol, Wiktor Majczak, René Heerlien, Jan Pieter van der Berg, Nico Nouwen, Arnold J M Driessen
Source: Journal of molecular biology. 2009 Jul 31
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