1 to 10 of 89 literature results

• A genome-wide linkage and association scan reveals novel loci for autism.

  Although autism is a highly heritable neurodevelopmental disorder, attempts to identify specific susceptibility genes have thus far met with limited s…

  Authors: Lauren A Weiss, Dan E Arking, Gene Discovery Project of Johns Hopkins & the Autism Consortium, Mark J Daly, Aravinda Chakravarti

  Source: Nature. 2009 Oct 8

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• Obituary: Victor Almon McKusick (1921-2008).

  Authors: Aravinda Chakravarti

  Source: Nature. 2008 Sep 4

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• Human genetics: Tracing India's invisible threads.

  Authors: Aravinda Chakravarti

  Source: Nature. 2009 Sep 24

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• Being human: kinship: race relations.

  Authors: Aravinda Chakravarti

  Source: Nature. 2009 Jan 22

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• Nature, nurture and human disease.

  What has been learnt about individual human biology and common diseases 50 years on from the discovery of the structure of DNA? Unfortunately the doub…

  Authors: Aravinda Chakravarti, Peter Little

  Source: Nature. 2003 Jan 23

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• Finding the missing heritability of complex diseases.

  Genome-wide association studies have identified hundreds of genetic variants associated with complex human diseases and traits, and have provided valu…

  Authors: Teri A Manolio, Francis S Collins, Nancy J Cox, David B Goldstein, Lucia A Hindorff, David J Hunter, Mark I McCarthy, Erin M Ramos, Lon R Cardon, Aravinda Chakravarti,…

  Source: Nature. 2009 Oct 8

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• Exhaustive allelic transmission disequilibrium tests as a new approach to genome-wide association studies.

  Genome-wide disease-association mapping has been heralded as the study design of the next generation, but the lack of analytical methods to use genoty…

  Authors: Shin Lin, Aravinda Chakravarti, David J Cutler

  Source: Nature genetics. 2004 Nov

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• A common sex-dependent mutation in a RET enhancer underlies Hirschsprung disease risk.

  The identification of common variants that contribute to the genesis of human inherited disorders remains a significant challenge. Hirschsprung diseas…

  Authors: Eileen Sproat Emison, Andrew S McCallion, Carl S Kashuk, Richard T Bush, Elizabeth Grice, Shin Lin, Matthew E Portnoy, David J Cutler, Eric D Green, Aravinda Chakravarti

  Source: Nature. 2005 Apr 14

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• Common variants at ten loci modulate the QT interval duration in the QTSCD Study.

  The QT interval, a measure of cardiac repolarization, predisposes to ventricular arrhythmias and sudden cardiac death (SCD) when prolonged or shortene…

  Authors: Arne Pfeufer, Serena Sanna, Dan E Arking, Martina Müller, Vesela Gateva, Christian Fuchsberger, Georg B Ehret, Marco Orrú, Cristian Pattaro, Anna Köttgen,…

  Source: Nature genetics. 2009 Apr

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• Common variants in KCNN3 are associated with lone atrial fibrillation.

  Atrial fibrillation (AF) is the most common sustained arrhythmia. Previous studies have identified several genetic loci associated with typical AF. We…

  Authors: Patrick T Ellinor, Kathryn L Lunetta, Nicole L Glazer, Arne Pfeufer, Alvaro Alonso, Mina K Chung, Moritz F Sinner, Paul I W de Bakker, Martina Mueller, Steven A Lubitz,…

  Source: Nature genetics. 2010 Mar

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