1 to 10 of 50 literature results

• Essential autocrine regulation by IL-21 in the generation of inflammatory T cells.

  After activation, CD4+ helper T (T(H)) cells differentiate into distinct effector subsets that are characterized by their unique cytokine expression a…

  Authors: Roza Nurieva, Xuexian O Yang, Gustavo Martinez, Yongliang Zhang, Athanasia D Panopoulos, Li Ma, Kimberly Schluns, Qiang Tian, Stephanie S Watowich, Anton M Jetten,…

  Source: Nature. 2007 Jul 26

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• Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages.

  After activation, CD4(+) helper T (Th) cells differentiate into distinct effector subsets. Although chemokine (C-X-C motif) receptor 5-expressing T fo…

  Authors: Roza I Nurieva, Yeonseok Chung, Daehee Hwang, Xuexian O Yang, Hong Soon Kang, Li Ma, Yi-hong Wang, Stephanie S Watowich, Anton M Jetten, Qiang Tian,…

  Source: Immunity. 2008 Jul 18

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• Critical regulation of early Th17 cell differentiation by interleukin-1 signaling.

  T helper (Th) 17 cells have been recently discovered in both mouse and human. Here we show that interleukin-1 (IL-1) signaling on T cells is criticall…

  Authors: Yeonseok Chung, Seon Hee Chang, Gustavo J Martinez, Xuexian O Yang, Roza Nurieva, Hong Soon Kang, Li Ma, Stephanie S Watowich, Anton M Jetten, Qiang Tian,…

  Source: Immunity. 2009 Apr 17

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• RAP80 responds to DNA damage induced by both ionizing radiation and UV irradiation and is phosphorylated at Ser 205.

  Receptor-associated protein (RAP80), a nuclear protein containing two ubiquitin-interacting motifs (UIM), was recently found to be associated with bre…

  Authors: Jun Yan, Xiao-Ping Yang, Yong-Sik Kim, Anton M Jetten

  Source: Cancer research. 2008 Jun 1

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• Glis3 is associated with primary cilia and Wwtr1/TAZ and implicated in polycystic kidney disease.

  In this study, we describe the generation and partial characterization of Krüppel-like zinc finger protein Glis3 mutant (Glis3(zf/zf)) mice. These mic…

  Authors: Hong Soon Kang, Ju Youn Beak, Yong-Sik Kim, Ronald Herbert, Anton M Jetten

  Source: Molecular and cellular biology. 2009 May

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• Molecular antagonism and plasticity of regulatory and inflammatory T cell programs.

  Regulatory T (Treg) and T helper 17 (Th17) cells were recently proposed to be reciprocally regulated during differentiation. To understand the underly…

  Authors: Xuexian O Yang, Roza Nurieva, Gustavo J Martinez, Hong Soon Kang, Yeonseok Chung, Bhanu P Pappu, Bhavin Shah, Seon Hee Chang, Kimberly S Schluns, Stephanie S Watowich,…

  Source: Immunity. 2008 Jul 18

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• T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma.

  T cell functional differentiation is mediated by lineage-specific transcription factors. T helper 17 (Th17) has been recently identified as a distinct…

  Authors: Xuexian O Yang, Bhanu P Pappu, Roza Nurieva, Askar Akimzhanov, Hong Soon Kang, Yeonseok Chung, Li Ma, Bhavin Shah, Athanasia D Panopoulos, Kimberly S Schluns,…

  Source: Immunity. 2008 Jan

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• Functional analysis of the zinc finger and activation domains of Glis3 and mutant Glis3(NDH1).

  The Krüppel-like zinc finger protein Gli-similar 3 (Glis3) plays a critical role in pancreatic development and has been implicated in a syndrome with …

  Authors: Ju Youn Beak, Hong Soon Kang, Yong-Sik Kim, Anton M Jetten

  Source: Nucleic acids research. 2008 Mar

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• Farnesol-induced apoptosis in human lung carcinoma cells is coupled to the endoplasmic reticulum stress response.

  Farnesol (FOH) and other isoprenoid alcohols induce apoptosis in various carcinoma cells and inhibit tumorigenesis in several in vivo models. However,…

  Authors: Joung Hyuck Joo, Grace Liao, Jennifer B Collins, Sherry F Grissom, Anton M Jetten

  Source: Cancer research. 2007 Aug 15

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• Molecular mechanisms involved in farnesol-induced apoptosis.

  The isoprenoid alcohol farnesol is an effective inducer of cell cycle arrest and apoptosis in a variety of carcinoma cell types. In addition, farnesol…

  Authors: Joung Hyuck Joo, Anton M Jetten

  Source: Cancer letters. 2010 Jan 28

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