1 to 5 of 5 literature results

• WNK4 regulates the balance between renal NaCl reabsorption and K+ secretion.

  A key question in systems biology is how diverse physiologic processes are integrated to produce global homeostasis. Genetic analysis can contribute b…

  Authors: Kristopher T Kahle, Frederick H Wilson, Qiang Leng, Maria D Lalioti, Anthony D O'Connell, Ke Dong, Alicia K Rapson, Gordon G MacGregor, Gerhard Giebisch, Steven C Hebert,…

  Source: Nature genetics. 2003 Dec

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• Selectivity and interactions of Ba2+ and Cs+ with wild-type and mutant TASK1 K+ channels expressed in Xenopus oocytes.

  The acid-sensitive K(+) channel, TASK1 is a member of the K(+)-selective tandem-pore domain (K2P) channel family. Like many of the K2P channels, TASK1…

  Authors: Anthony D O'Connell, Michael J Morton, Asipu Sivaprasadarao, Malcolm Hunter

  Source: The Journal of physiology. 2005 Feb 1

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• Phosphorylation-regulated endoplasmic reticulum retention signal in the renal outer-medullary K+ channel (ROMK).

  The renal outer-medullary K+ channel (ROMK; Kir1.1) mediates K+ secretion in the renal mammalian nephron that is critical to both sodium and potassium…

  Authors: Anthony D O'Connell, Qiang Leng, Ke Dong, Gordon G MacGregor, Gerhard Giebisch, Steven C Hebert

  Source: Proceedings of the National Academy of Sciences of the United States of America. 2005 Jul 12

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• Determinants of pH sensing in the two-pore domain K(+) channels TASK-1 and -2.

  TASK-1 and -2 are members of the two-pore domain potassium (K(+)) channel family and are sensitive to changes in extracellular pH. The effects of muta…

  Authors: Michael J Morton, Anthony D O'Connell, Asipu Sivaprasadarao, Malcolm Hunter

  Source: Pflügers Archiv : European journal of physiology. 2003 Feb

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• Two-pore domain K+ channels-molecular sensors.

  Two-pore domain K(+) (K2P) channels have been cloned from a variety of species and tissues. They have been characterised biophysically as a 'backgroun…

  Authors: Anthony D O'Connell, Michael J Morton, Malcolm Hunter

  Source: Biochimica et biophysica acta. 2002 Nov 13

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