10 literature results

• Effects of long-term fenofibrate treatment on markers of renal function in type 2 diabetes: the FIELD Helsinki substudy.

  OBJECTIVE: Although fenofibrate was associated with less progression of albuminuria in the Fenofibrate Intervention and Event Lowering in Diabetes (FI…

  Authors: Carol Forsblom, Anne Hiukka, Eeva S Leinonen, Jouko Sundvall, Per-Henrik Groop, Marja-Riitta Taskinen

  Source: Diabetes care. 2010 Feb

  View Full Text

• ApoCIII-enriched LDL in type 2 diabetes displays altered lipid composition, increased susceptibility for sphingomyelinase, and increased binding to biglycan.

  OBJECTIVE: Apolipoprotein CIII (apoCIII) is an independent risk factor for cardiovascular disease, but the molecular mechanisms involved are poorly un…

  Authors: Anne Hiukka, Marcus Ståhlman, Camilla Pettersson, Malin Levin, Martin Adiels, Susanne Teneberg, Eeva S Leinonen, Lillemor Mattsson Hultén, Olov Wiklund, Matej Oresic,…

  Source: Diabetes. 2009 Sep

  View Full Text

• Long-term effects of fenofibrate on carotid intima-media thickness and augmentation index in subjects with type 2 diabetes mellitus.

  OBJECTIVES: The aim of this substudy was to ascertain whether long-term treatment with fenofibrate reduces surrogate measures of atherosclerosis, biom…

  Authors: Anne Hiukka, Jukka Westerbacka, Eeva S Leinonen, Hiroshi Watanabe, Olov Wiklund, Lillemor Mattson Hulten, Jukka T Salonen, Tomi-Pekka Tuomainen, Hannele Yki-Järvinen, Anthony C Keech,…

  Source: Journal of the American College of Cardiology. 2008 Dec 16

  View Full Text

• Alterations of lipids and apolipoprotein CIII in very low density lipoprotein subspecies in type 2 diabetes.

  AIMS/HYPOTHESIS: Very low density lipoprotein (VLDL) particles are heterogeneous, comprising two main subspecies, VLDL 1 (Sf 60-400) and VLDL 2 (Sf 20…

  Authors: Anne Hiukka, Jamila Fruchart-Najib, Eeva Leinonen, Hannele Hilden, Jean-Charles Fruchart, Marja-Riitta Taskinen

  Source: Diabetologia. 2005 Jun

  View Full Text

• Serum, but not monocyte macrophage foam cells derived from low HDL-C subjects, displays reduced cholesterol efflux capacity.

  The main antiatherogenic function of HDL is to promote the efflux of cholesterol from peripheral cells and transport it to the liver for excretion in …

  Authors: Shuhei Nakanishi, Riikka Vikstedt, Sanni Söderlund, Miriam Lee-Rueckert, Anne Hiukka, Christian Ehnholm, Mikko Muilu, Jari Metso, Jussi Naukkarinen, Leena Palotie,…

  Source: Journal of lipid research. 2009 Feb

  View Full Text

• Common ABCA1 variants, HDL levels, and cellular cholesterol efflux in subjects with familial low HDL.

  HDL promotes cholesterol efflux from peripheral cells via ABCA1 in the first step of reverse cholesterol transport (RCT). We investigated whether the …

  Authors: Aino Soro-Paavonen, Jussi Naukkarinen, Miriam Lee-Rueckert, Hiroshi Watanabe, Elina Rantala, Sanni Soderlund, Anne Hiukka, Petri T Kovanen, Matti Jauhiainen, Leena Peltonen,…

  Source: Journal of lipid research. 2007 Jun

  View Full Text

• Insulin resistance and adiposity correlate with acute-phase reaction and soluble cell adhesion molecules in type 2 diabetes.

  OBJECTIVE: To investigate the relationship of inflammation and endothelial activation with insulin resistance and adiposity in type 2 diabetes. METHOD…

  Authors: Eeva Leinonen, Eva Hurt-Camejo, Olov Wiklund, Lillemor Mattson Hultén, Anne Hiukka, Marja-Riitta Taskinen

  Source: Atherosclerosis. 2003 Feb

  View Full Text

• Acute exposure to rosiglitazone does not affect glucose transport in intact human skeletal muscle.

  Thiazolidinediones (TZDs) such as rosiglitazone are widely used as antidiabetic drugs. Animal studies suggest that TZDs may have direct metabolic acti…

  Authors: Paulina Skrobuk, Heidi Kuoppamaa, Anne Hiukka, Heikki A Koistinen

  Source: Metabolism: clinical and experimental. 2010 Feb

  View Full Text

• Globular adiponectin stimulates glucose transport in type 2 diabetic muscle.

  BACKGROUND: Adiponectin acts as an insulin sensitizer in rodent models. The direct effect of adiponectin in intact type 2 diabetic muscle is unknown. …

  Authors: Heidi Kuoppamaa, Paulina Skrobuk, Maarit Sihvo, Anne Hiukka, Alexander V Chibalin, Juleen R Zierath, Heikki A Koistinen

  Source: Diabetes/metabolism research and reviews. 2008 Oct

  View Full Text

• Decreased high-density lipoprotein (HDL) particle size, prebeta-, and large HDL subspecies concentration in Finnish low-HDL families: relationship with intima-media thickness.

  OBJECTIVE: High-density lipoprotein (HDL) cholesterol correlates inversely with the risk of coronary heart disease (CHD). The precise antiatherogenic …

  Authors: Hiroshi Watanabe, Sanni Söderlund, Aino Soro-Paavonen, Anne Hiukka, Eeva Leinonen, Corradina Alagona, Riitta Salonen, Tomi-Pekka Tuomainen, Christian Ehnholm, Matti Jauhiainen,…

  Source: Arteriosclerosis, thrombosis, and vascular biology. 2006 Apr

  View Full Text