1 to 10 of 28 literature results

• Inside, outside, upside down: damage-associated molecular-pattern molecules (DAMPs) and redox.

  Immune responses are initiated and perpetuated by molecules derived from microorganisms pathogen-associated molecular-pattern molecules or from the da…

  Authors: Anna Rubartelli, Michael T Lotze

  Source: Trends in immunology. 2007 Oct

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• NK/iDC interaction results in IL-18 secretion by DCs at the synaptic cleft followed by NK cell activation and release of the DC maturation factor HMGB1.

  Interaction of natural killer (NK) cells with autologous immature dendritic cells (DCs) results in reciprocal activation; however, the underlying mech…

  Authors: Claudia Semino, Giovanna Angelini, Alessandro Poggi, Anna Rubartelli

  Source: Blood. 2005 Jul 15

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• Stress as an intercellular signal: the emergence of stress-associated molecular patterns (SAMP).

  Abstrct Cells are continuously exposed to stressful situations that generally entail generation of reactive oxygen species and other redox alterations…

  Authors: Anna Rubartelli, Roberto Sitia

  Source: Antioxidants & redox signaling. 2009 Oct

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• Differential requirement for the activation of the inflammasome for processing and release of IL-1beta in monocytes and macrophages.

  The processing of pro-interleukin-1beta depends on activation of caspase-1. Controversy has arisen whether Toll-like receptor (TLR) ligands alone can …

  Authors: Mihai G Netea, Claudia A Nold-Petry, Marcel F Nold, Leo A B Joosten, Bastian Opitz, Jonathan H M van der Meer, Frank L van de Veerdonk, Gerben Ferwerda, Bas Heinhuis, Isabel Devesa,…

  Source: Blood. 2009 Mar 5

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• Histone deacetylase inhibitors prevent exocytosis of interleukin-1beta-containing secretory lysosomes: role of microtubules.

  A number of agents reducing interleukin-1beta (IL-1beta) activity are being developed as novel immunomodulatory and anti-inflammatory therapies. Howev…

  Authors: Sonia Carta, Sara Tassi, Claudia Semino, Gianluca Fossati, Paolo Mascagni, Charles A Dinarello, Anna Rubartelli

  Source: Blood. 2006 Sep 1

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• DAMPs and inflammatory processes: the role of redox in the different outcomes.

  Inflammation is deeply entangled with redox modulation. Triggering of PRRs on inflammatory cells induces ROS generation. As a consequence, activated c…

  Authors: Sonia Carta, Patrizia Castellani, Laura Delfino, Sara Tassi, Roberta Venè, Anna Rubartelli

  Source: Journal of leukocyte biology. 2009 Sep

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• The thiol redox state of lymphoid organs is modified by immunization: role of different immune cell populations.

  Resting T lymphocytes can internalize reduced cysteine (Cys) but not cystine, the oxidized form of the amino acid that predominates extracellularly. I…

  Authors: Patrizia Castellani, Giovanna Angelini, Laura Delfino, Andrea Matucci, Anna Rubartelli

  Source: European journal of immunology. 2008 Sep

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• The grateful dead: damage-associated molecular pattern molecules and reduction/oxidation regulate immunity.

  The response to pathogens and damage in plants and animals involves a series of carefully orchestrated, highly evolved, molecular mechanisms resulting…

  Authors: Michael T Lotze, Herbert J Zeh, Anna Rubartelli, Louis J Sparvero, Andrew A Amoscato, Newell R Washburn, Michael E Devera, Xiaoyan Liang, Mahmut Tör, Timothy Billiar

  Source: Immunological reviews. 2007 Dec

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• Pattern of interleukin-1beta secretion in response to lipopolysaccharide and ATP before and after interleukin-1 blockade in patients with CIAS1 mutations.

  OBJECTIVE: To examine the synthesis, processing, and secretion of interleukin-1beta (IL-1beta), as well as the clinical and biologic effects of IL-1 b…

  Authors: Marco Gattorno, Sara Tassi, Sonia Carta, Laura Delfino, Francesca Ferlito, Maria Antonietta Pelagatti, Andrea D'Osualdo, Antonella Buoncompagni, Maria Giannina Alpigiani, Maria Alessio,…

  Source: Arthritis and rheumatism. 2007 Sep

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• The maturation potential of NK cell clones toward autologous dendritic cells correlates with HMGB1 secretion.

  Interaction of NK cells with autologous immature dendritic cells (iDCs) results in reciprocal activation. We have previously reported that NK cells tr…

  Authors: Claudia Semino, Jenny Ceccarelli, Lavinia V Lotti, Maria R Torrisi, Giovanna Angelini, Anna Rubartelli

  Source: Journal of leukocyte biology. 2007 Jan

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